Table 2 The MMSE, GDS-15, and NfL levels between MDD and MCI/AD

MMSE, Maximum score (SD)

MMSE total, 30^a

27.13 (2.56)

22.33 (3.42)

<0.001***

 Orientation, 10

9.44 (0.94)

7.60 (1.60)

<0.001***

 Attention and calculation, 8

7.10 (1.21)

5.40 (1.12)

<0.001***

 Memory, 3

2.10 (0.99)

1.53 (1.25)

0.085

 Language, 5

4.72 (0.69)

4.80 (0.86)

0.716

 Comprehension, 3

2.79 (0.47)

2.06 (0.88)

0.008**

 Construction, 1

0.97 (0.16)

0.93 (0.26)

0.573

GDS-15 (SD)^a

5.94 (4.36)

3.20 (2.96)

0.032*

NfL levels (SD)

15.69 (8.81)

28.95 (17.04)

0.012*