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Fig. 1 | BMC Geriatrics

Fig. 1

From: The causal relationship of human blood metabolites with the components of Sarcopenia: a two-sample Mendelian randomization analysis

Fig. 1

Overview of the current Mendelian randomization (MR) study. Notes: SNP, Single nucleotide polymorphism; LD, Linkage disequilibrium; IVW, Inverse-variance weighted; WM, Weighted median; LOO analysis, Leave-one-out sensitivity analysis; MR-PRESSO, Mendelian Randomization Pleiotropy RESidual Sum and Outlier. *Three assumptions that a Mendelian randomization study should satisfy: assumption 1, the genotype was related to the exposure(relevance assumption); assumption 2, the association of the genotype with the outcome was independent of the other confounding factors (independence assumption); assumption 3, the genotype was associated with the outcome only by the exposure studied (exclusivity assumption)

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BMC Geriatrics

ISSN: 1471-2318

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