Association between symptoms of depression and inflammatory parameters in people aged over 90 years

BMC Geriatrics

Table 3 Testing for significant variables in the relationship between depression severity and selected blood parameters

Factors	GDS	N	Median	Q1–Q3	min–max	Kruskal-Wallis test; p-value	FDR
TNF_α (pg/mL)	MAJOR DEPRESSION	19	8.70	6.96–10.51	5.17–27.04	H = 0.975 p = 0.615	0.958
	MODERATE DEPRESSION	36	7.89	5.57–11.66	1.23–69.06
	NO DEPRESSION	35	8.92	5.89–13.45	2.39–67.37
TGF_β1 (pg/mL)	MAJOR DEPRESSION	19	19	38,910	27778.50-59460.00	H = 0.793 p = 0.673	0.958
	MODERATE DEPRESSION	36	36	35,385	29551.50-44310.00
	NO DEPRESSION	35	35	39,960	28994.25–47370.00
CRP (mg/L)	MAJOR DEPRESSION	19	10.29	5.45–16.45	1.50-33.57	H = 3.644; p = 0.162	0.958
	MODERATE DEPRESSION	36	4.86	2.29–11.08	1.02–46.29
	NO DEPRESSION	35	7.91	3.44–13.65	0.74–44.39
Fibrinogen (µg/mL)	MAJOR DEPRESSION	19	40.89	40.81–41.05	40.73–41.14	H = 2.735 p = 0.255	0.958
	MODERATE DEPRESSION	36	40.89	40.73–41.05	4.19–41.14
	NO DEPRESSION	35	40.97	40.89–41.05	5.83–41.22
IL_10 (pg/mL)	MAJOR DEPRESSION	19	1.60	1.60–8.22	1.60-129.40	H = 1.0061 p = 0.605	0.958
	MODERATE DEPRESSION	36	4.07	1.60-28.45	1.60-631.70
	NO DEPRESSION	35	3.11	1.60-17.52	1.60–76.20
IL_1α (pg/mL)	MAJOR DEPRESSION	19	1.10	1.10–1.10	1.10–1.92	H = 0.203 p = 0.904	0.958
	MODERATE DEPRESSION	36	1.10	1.10–1.11	1.10-10.19
	NO DEPRESSION	35	1.10	1.10–1.10	1.10-23.260
IL_1β (pg/mL)	MAJOR DEPRESSION	19	0.35	0.35–0.35	0.35–293.10	H = 0.445 p = 0.799	0.958
	MODERATE DEPRESSION	36	0.35	0.35–0.35	0.35–1355
	NO DEPRESSION	35	0.35	0.35–0.35	0.35–748.40
IL_6 (pg/mL)	MAJOR DEPRESSION	19	20.27	12.49–46.09	7.46–437.40	H = 0.086 p = 0.958	0.958
	MODERATE DEPRESSION	36	22.36	13.20-51.12	2-668.80
	NO DEPRESSION	35	27.16	7.82–57.95	2-596

Q1– First Quartile; Q3– Third Quartile; N- number of population; min-minimum; max-maximum;FDR - false discovery rate

ISSN: 1471-2318