Influence of chronic medical conditions on older patients’ willingness to deprescribe medications: a cross-sectional study

Table 3 Associations between chronic medical conditions and older patients’ willingness to have medications deprescribed (N = 192) ^a

Variable	P value	aOR	95% CI
Variable	P value	aOR	Lower	Upper
Age (years)	0.034	1.121	1.009	1.246
Gastric disease ^c	0.022	4.123	1.221	13.915
Prostatic disease^d	0.036	0.266	0.077	0.916
rPATD appropriateness factor	0.007	0.384	0.190	0.773
rPATD concerns about stopping factor	0.020	0.450	0.229	0.883
Constant	0.852	0.473

aOR: adjusted odds ratio; CI: confidence interval; rPATD: revised Patients’ Attitudes Towards Deprescribing
a) Multiple logistic binary regression with backward LR method. The rPATD global question “If my doctor said it was possible, I would be willing to stop one or more of my regular medicines” was dichotomized to a binary outcome: agree (strongly agree or agree) and disagree (unsure, disagree, or strongly disagree), designated as “willingness to have medications deprescribed.” As independent variables to include in the multiple binary logistic regression model, we selected the patients’ demographic and clinic characteristics, the independent variables with p < 0.100 in bivariate analysis, and the variable age, which was considered clinically relevant
b) All assumptions were satisfied for the selected variables, except for the rPATD appropriateness factor score. However, it was included in the multiple binary regression because it was considered a clinically relevant variable
c) Any history of ulcer disease treatment or prevention, ulcer bleeding, or GERD (gastroesophageal reflux disease)
d) Prostate benign hypertrophy and prostatic neoplasia

ISSN: 1471-2318