All participants (n = 24) | p | LF (n = 13) | HF (n = 11) | p | |||
---|---|---|---|---|---|---|---|
PRE | POST | Δ (95%CI) | Δ (95%CI) | Δ (95%CI) | |||
Indicators of iron metabolism | |||||||
Iron (µg/dl) | 98.83 ± 25.48 | 95.21 ± 26.75 | –3.63 (–17.2; 9.95) | 0.75 | 3.15 (–12.85; 19.16) | –11.64 (–36.82; 13.55) | 0.27 |
Ferritin (ng/ml) | 113.3 ± 90.67 | 96.42 ± 78.64* | –16.88 (–28.85; − 4.91) | 0.01 | –6.05 (–13.98; 1.89) | –29.68 (–53.98; − 5.38) | 0.04 |
Tf (g/l) | 2.76 ± 0.28 | 2.73 ± 0.28 | –0.02 (–0.1; 0.05) | 0.52 | –0.03 (–0.14; 0.07) | –0.01 (–0.13; 0.11) | 0.75 |
Body iron (mg/kg) | 38.99 ± 2.69 | 38.07 ± 2.77 | –0.93 (–1.41; − 0.44) | < 0.01 | –0.73 (–1.49; 0.02) | –1.15 (–1.86; − 0.45) | 0.39 |
sTfR (mg/l) | 1.2 ± 0.29 | 1.32 ± 0.37 | 0.12 (0.03; 0.22) | 0.01 | 0.1 (–0.02; 0.22) | 0.15 (–0.02; 0.33) | 0.59 |
Haematological indicators | |||||||
Hb (g/dl) | 13.98 ± 1.06 | 13.62 ± 0.97* | –0.36 (–0.52; − 0.2) | < 0.01 | –0.33 (–0.59; − 0.07) | –0.4 (–0.61; − 0.19) | 0.66 |
HbA1c (mmol/mol) | 42.08 ± 5.46 | 39.17 ± 5.01* | –2.92 (–3.79; -2.05) | < 0.01 | –2.31 (–3.31; − 1.31) | –3.64 (–5.21; − 2.07) | 0.12 |
HbA1c (%) | 5.98 ± 0.5 | 5.73 ± 0.47* | –0.25 (–0.26; − 0.14) | < 0.01 | –0.22 (–0.3; − 0.13) | –0.3 (–0.45; − 0.15) | 0.27 |
RBC (T/l) | 4.58 ± 0.35 | 4.49 ± 0.35* | –0.09 (–0.19; − 0.1) | < 0.01 | –0.09 (–0.18; − 0.01) | –0.09 (–0.17; 0) | 0.88 |
Ht (%) | 42.05 ± 2.6 | 41.1 ± 2.66 | –0.96 (–1.95; − 1.08) | 0.01 | –1.12 (–2.05; − 0.2) | –0.76 (–1.61; 0.08) | 0.54 |
MCV (fl.) | 92.03 ± 3.19 | 91.72 ± 3.34 | –0.32 (–2.45; − 1.36) | 0.38 | –0.61 (–1.75; 0.54) | 0.03 (–1.03; 1.09) | 0.39 |
MCH (pg) | 30.56 ± 1.27 | 30.38 ± 1.31 | –0.18 (–0.74; − 0.41) | 0.12 | –0.09 (–0.45; 0.27) | –0.27 (–0.57; 0.03) | 0.42 |
MCHC (g/dl) | 33.23 ± 0.97 | 33.13 ± 0.64 | –0.1 (–1.07; − 0.59) | 0.54 | 0.1 (–0.42; 0.62) | –0.33 (–0.72; 0.06) | 0.18 |
WBC (G/l) | 5.53 ± 1.23 | 5.77 ± 1.2 | 0.24 (0.45;0.82) | 0.06 | 0.37 (0.11;0.64) | 0.09 (–0.39;0.57) | 0.25 |
Biochemical indicators | |||||||
SII (cells/l) | 414.42 ± 211.46 | 370.43 ± 191.39 | –43.99 (–107.6; 19.61) | 0.41 | –55.68 (–148.86; 37.5) | –30.18 (–132.65; 72.28) | 0.69 |
AspAT (U/l) | 23.58 ± 5.56 | 24.5 ± 5.44 | 0.92 (–0.8; 2.63) | 0.28 | 2.62 (0.17; 5.06) | –1.09 (–3.22; 1.04) | 0.02 |
ALT (U/l) | 24.17 ± 10.66 | 24.29 ± 10.07 | 0.12 (–2.06; 2.31) | 0.91 | 2.77 (–0.11; 5.65) | –3 (–5.57; − 0.43) | < 0.01 |
Glucose (mg/dl) | 101.83 ± 24.06 | 98.42 ± 21.84 | –3.42 (–6.82; − 0.01) | 0.05 | –3.77 (–8.2; 0.66) | –3 (–9.19; 3.19) | 0.82 |
TC (mg/dl) | 197.17 ± 45.32 | 196.17 ± 44.77 | –1 (–10.87; 8.87) | 0.84 | 0.38 (–15.26; 16.03) | –2.64 (–16.84; 11.56) | 0.76 |
TG (mg/dl) | 111.42 ± 44.4 | 107.58 ± 58.91 | –3.83 (–20.81; 13.15) | 0.64 | –1.77 (–27.75; 24.21) | –6.27 (–32.2; 19.65) | 0.79 |
HDL-C (mg/dl) | 62.42 ± 15.44 | 61.42 ± 13.15 | –1 (–4.52; 2.52) | 0.56 | –2.77 (–7.9; 2.36) | 1.09 (–4.3; 6.48) | 0.27 |
LDL-C (mg/dl) | 112.5 ± 40.99 | 113.21 ± 39.2 | 0.71 (–7.58; 9) | 0.86 | 3.46 (–9.13; 16.06) | –2.55 (–15.01; 9.92) | 0.47 |