Worse | Stable | Improved | p value | |
---|---|---|---|---|
Total sample (n = 1022) | ||||
N (%) | 121 (11.8) | 686 (67.1) | 215 (21.0) | |
Age, M (SD) | 66.6 (7.0) | 67.4 (7.2) | 66.9 (7.5) | 0.507 |
Female, N (%) | 74 (61.2) | 411 (59.9) | 133 (61.9) | 0.866 |
Years of education, M (SD) | 13.5 (4.0) | 13.2 (4.1) | 13.4 (3.9) | 0.591 |
MMSE score, M (SD) | 29.5 (0.8) | 29.3 (0.8) | 29.4 (0.8) | 0.192 |
APOE E4 carrier, N (%) | 29 (24.0) | 201 (29.3) | 68 (31.8) | 0.335 |
CVD, N (%) | 13 (10.7) | 76 (11.1) | 19 (8.8) | 0.646 |
LS7, M (SD) | 9.3 (1.8) | 7.8 (1.7) | 6.5 (1.7) | < 0.001 |
BMI poor, N (%) | 10 (8.3) | 91 (13.3) | 38 (17.7) | 0.005 |
smoking poor, N (%) | 13 (10.7) | 77 (11.2) | 50 (23.3) | < 0.001 |
physical activity poor, N (%) | 3 (2.5) | 85 (12.3) | 47 (21.9) | < 0.001 |
cholesterol poor, N (%) | 34 (28.1) | 273 (39.8) | 129 (60.0) | < 0.001 |
glucose poor, N (%) | 5 (4.1) | 39 (5.7) | 14 (6.5) | 0.022 |
blood pressure poor, N (%) | 39 (32.2) | 436 (63.6) | 153 (71.2) | < 0.001 |
diet poor, N (%) | 15 (12.4) | 170 (24.8) | 105 (48.8) | < 0.001 |
new antihypertensive medication at FU, N (%) | 19 (15.7) | 134 (19.5) | 41 (19.1) | 0.612 |
new anticholesterol medication at FU, N (%) | 11 (9.1) | 84 (12.2) | 48 (22.3) | < 0.001 |
Young-old (n = 864) | ||||
N (%) | 103 (11.9) | 579 (67.0) | 182 (21.1) | |
Age, M (SD) | 64.3 (4.5) | 65.0 (4.7) | 64.3 (4.5) | 0.143 |
Female, N (%) | 64 (62.1) | 340 (58.7) | 114 (62.6) | 0.572 |
Years of education, M (SD) | 13.4 (4.1) | 13.4 (4.0) | 13.6 (3.9) | 0.92 |
MMSE score, M (SD) | 29.5 (0.8) | 29.4 (0.8) | 29.5 (0.7) | 0.476 |
APOE E4 carrier, N (%) | 26 (25.2) | 172 (29.7) | 60 (33.1) | 0.402 |
CVD, N (%) | 10 (9.7) | 56 (9.7) | 10 (5.5) | 0.209 |
LS7, M (SD) | 9.2 (1.8) | 7.9 (1.7) | 6.5 (1.8) | < 0.001 |
BMI poor, N (%) | 9 (8.7) | 77 (13.3) | 30 (16.5) | 0.038 |
smoking poor, N (%) | 13 (12.6) | 71 (12.3) | 49 (26.9) | < 0.001 |
physical activity poor, N (%) | 3 (2.9) | 73 (12.6) | 41 (22.5) | < 0.001 |
cholesterol poor, N (%) | 29 (28.2) | 232 (40.1) | 109 (59.9) | < 0.001 |
glucose poor, N (%) | 4 (3.9) | 29 (5.0) | 13 (7.1) | 0.064 |
blood pressure poor, N (%) | 23 (33.0) | 350 (60.4) | 124 (68.1) | < 0.001 |
diet poor, N (%) | 14 (13.6) | 151 (26.1) | 90 (49.5) | < 0.001 |
new antihypertensive medication at FU, N (%) | 13 (12.6) | 109 (18.8) | 34 (18.7) | 0.311 |
new anticholesterol medication at FU, N (%) | 9 (8.7) | 66 (11.4) | 39 (21.4) | 0.001 |
Old-old (n = 158) | ||||
N (%) | 18 (11.4) | 107 (67.7) | 33 (20.9) | |
Age, M (SD) | 79.9 (2.2) | 80.5 (3.1) | 81.4 (3.1) | 0.162 |
Female, N (%) | 10 (55.6) | 71 (66.4) | 19 (57.6) | 0.507 |
Years of education, M (SD) | 14.1 (3.9) | 11.8 (4.0) | 12.4 (3.9) | 0.085 |
MMSE score, M (SD) | 29.3 (0.8) | 28.9 (1.0) | 29.1 (0.9) | 0.299 |
APOE E4 carrier, N (%) | 3 (16.7) | 29 (27.4) | 8 (24.2) | 0.619 |
CVD, N (%) | 3 (16.7) | 20 (18.7) | 9 (27.3) | 0.519 |
LS7, M (SD) | 9.6 (1.5) | 7.6 (1.5) | 6.6 (1.5) | < 0.001 |
BMI poor, N (%) | 1 (5.6) | 14 (13.1) | 8 (24.2) | 0.2 |
smoking poor, N (%) | 0 (0.0) | 6 (5.6) | 1 (3.0) | 0.648 |
physical activity poor, N (%) | 0 (0.0) | 12 (11.2) | 6 (18.2) | 0.145 |
cholesterol poor, N (%) | 5 (27.8) | 41 (38.3) | 20 (60.6) | 0.019 |
glucose poor, N (%) | 1 (5.6) | 10 (9.3) | 1 (3.0) | 0.208 |
blood pressure poor, N (%) | 5 (27.8) | 86 (80.4) | 29 (87.9) | < 0.001 |
diet poor, N (%) | 1 (5.6) | 19 (17.8) | 15 (45.5) | 0.004 |
new antihypertensive medication at FU, N (%) | 6 (33.3) | 25 (23.4) | 7 (21.2) | 0.6 |
new anticholesterol medication at FU, N (%) | 2 (11.1) | 18 (16.8) | 9 (27.3) | 0.28 |