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Table 1 Weighted characteristics of the participants by serum soluble alpha-klotho quartilea

From: Serum soluble alpha-klotho klotho and cognitive functioning in older adults aged 60 and 79: an analysis of cross-sectional data of the National Health and Nutrition Examination Survey 2011 to 2014

 

Quartile 1

< 657.8pg/mL (n = 537)

Quartile 2

657.8 -797.7pg/mL (n = 510)

Quartile 3

797.8-958.2 pg/mL (n = 525)

Quartile 4

≥ 958.3 pg/mL (n = 601)

Total

(n = 2,173)

P-value for linear trend

Weighted number of participants

10,242,822

10,232,107

10,227,089

10,270,606

40,972,624

-

Age, years

68.1 (0.3)

67.5 (0.3)

67.1 (0.4)

67.1 (0.2)

67.4 (0.2)

0.01

Female, n (%)

271 (52.1)

242 (49.9)

269 (52.4)

337 (57.9)

1,119 (53.1)

0.03

Race/ethnicity, n (%)

     

0.55

 Mexican Americans

53 (3.6)

54 (3.5)

57 (3.9)

67 (4.5)

231 (3.9)

 

 Other Hispanics

44 (2.9)

58 (3.6)

68 (4.4)

79 (4.9)

249 (4.0)

 

 Non-Hispanic Whites

253 (79.4)

232 (80.9)

227 (79.7)

218 (74.5)

930 (78.6)

 

 Non-Hispanic Blacks

134 (8.2)

114 (7.3)

105 (6.5)

175 (10.8)

528 (8.2)

 

 Other

53 (5.8)

52 (4.7)

68 (5.5)

62 (5.4)

235 (5.4)

 

Education, n (%)

     

0.45

 Below high school

153 (17.4)

151 (17.8)

132 (13.1)

155 (16.1)

591 (16.1)

 

 High school graduate

125 (23.9)

106 (19.5)

114 (19.0)

146 (23.8)

491 (21.6)

 

 Some college or above

259 (58.7)

253 (62.7)

279 (68.0)

300 (60.1)

1,091 (62.4)

 

CES-D score

2.9 (0.2)

2.8 (0.2)

2.9 (0.3)

2.8 (0.2)

2.8 (0.1)

0.81

Smoking status, n (%)

     

0.59

 Never

249 (48.1)

221 (46.6)

262 (51.2)

327 (50.1)

1,059 (49.0)

 

 Former

211 (39.0)

208 (42.2)

191 (37.7)

193 (35.6)

803 (38.6)

 

 Current

77 (12.9)

80 (11.2)

72 (11.2)

81 (14.4)

310 (12.4)

 

Body mass index, n (%)

     

0.15

 <18.5 kg/m2

6 (0.5)

6 (1.2)

5 (1.2)

5 (1.5)

22 (1.1)

 

 18.5–24.9 kg/m2

120 (19.4)

114 (22.0)

125 (22.9)

152 (25.5)

511 (22.5)

 

 25.0-29.9 kg/m2

187 (38.7)

191 (39.0)

183 (35.1)

203 (34.2)

764 (36.7)

 

 ≥30 kg/m2

217 (41.3)

194 (37.8)

206 (40.8)

238 (38.8)

855 (39.7)

 

Physical activity, hours/week

1.1 (0.1)

1.3 (0.1)

1.4 (0.1)

1.3 (0.1)

1.3 (0.1)

0.28

Stroke, n (%)

42 (6.8)

34 (6.2)

31 (5.9)

31 (4.1)

138 (5.7)

0.13

Prevalent coronary heart disease, n (%)

50 (9.2)

47 (9.3)

42 (8.8)

25 (4.8)

164 (8.0)

0.03

Total cholesterol, mg/dL

190.9 (3.7)

193.9 (3.5)

195.9 (2.0)

195.7 (2.6)

194.1 (1.3)

0.12

Systolic blood pressure, mmHg

130.4 (1.3)

130.7 (1.0)

129.7 (1.3)

131.0 (1.1)

130.4 (0.5)

0.89

CERAD W-L immediate recall

19.9 (0.3)

19.8 (0.3)

20.1 (0.3)

20.3 (0.3)

20.0 (0.2)

0.15

CERAD W-L delayed recall

6.3 (0.2)

6.4 (0.2)

6.6 (0.2)

6.5 (0.1)

6.4 (0.1)

0.10

Animal fluency test

18.2 (0.3)

18.6 (0.3)

19.0 (0.4)

18.2 (0.3)

18.5 (0.2)

0.72

Digit Symbol Substitution Test

51.8 (0.9)

54.7 (1.0)

56.1 (1.1)

54.8 (1.0)

54.4 (0.6)

0.02

  1. a. Data was presented as mean (standard deviation) for continuous variables and n (%) for categorical variables
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