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Table 2 Characteristics of the four subject groups, stratified by FSH

From: A low follicle-stimulating hormone level is a protective factor for non-alcoholic fatty liver disease in older men aged over 80

Variable

Q1

Q2

Q3

Q4

P

N

110

110

110

114

 

FSH (IU/L)

9.61 (7.40–11.41)

14.82 (13.96–16.94)

25.12 (21.43–32.35)

51.6 (42.85–64.94)

 

Age (years)

84 (81–87)

85 (83–89)

85 (83–89)

88 (85–91)

< 0.001

BMI (kg/m2)

24.3 ± 3.0

25.0 ± 3.5

23.5 ± 3.4

24.0 ± 3.6

0.020

WC (cm)

91 ± 8

93 ± 8

90 ± 11

90 ± 11

0.014

SBP (mmHg)

137 ± 22

133 ± 22

133 ± 19

134 ± 19

0.425

DBP (mmHg)

71 ± 12

70 ± 12

66 ± 11

70 ± 11

0.030

Diabetes (%)

34.5

36.4

47.3

35.1

0.166

Hypertension (%)

85.5

78.2

89.1

80.7

0.130

Current/ex-smoker (%)

24.5

25.5

25.9

33.3

0.426

High education (%)

87.8

88.9

88.5

63.2

< 0.001

Married status (%)

92.2

94.4

92.7

89.5

0.579

Routine exercisea

44.9

40.0

41.2

42.1

0.912

MNA-SF score

13.0 (11.0–14.0)

13.0 (12.0–14.0)

12.0 (11.0–13.0)

12.0 (10.0–14.0)

0.034

Lipid-lowering drug users (%)

50.9

52.7

58.2

56.1

0.697

Antihypertensive drug users (%)

60

60

70.9

68.4

0.197

TT (nmol/L)

14.7 (8.0–19.5)

13.3 (9.3–18.4)

10.4 (7.9–15.0)

9.3 (6.3–12.6)

< 0.001

E2 (pmol/L)

141 (124–174)

153 (119–188)

121 (99–152)

109 (89–143)

< 0.001

LH (IU/L)

6.0 (4.7–8.3)

8.5 (6.2–10.5)

12.1 (8.1–17.3)

25.7 (22.3–35.8)

< 0.001

HbA1c (%)

5.7 (5.6–6.1)

5.9 (5.4–6.7)

6.0 (5.6–6.5)

5.9 (5.5–6.2)

0.191

FPG (mmol/L)

5.2 (4.6–5.7)

5.1 (4.8–5.8)

5.4 (4.8–6.4)

5.2 (4.8–5.6)

0.373

FINS (pmol/L)

6.4 (4.3–10.5)

8.1 (5.2–11.1)

7.1 (4.0–12.0)

6.8 (4.8–11.3)

0.312

TC (mmol/L)

3.74 (3.22–4.46)

4.06 (3.30–4.70)

4.00 (3.34–4.94)

3.89 (3.39–4.39)

0.143

TG (mmol/L)

0.83 (0.61–1.19)

1.08 (0.81–1.45)

1.04 (0.68–1.36)

1.07 (0.83–1.42)

0.004

LDL-c (mmol/L)

2.00 (1.70–2.47)

2.24 (1.63–2.89)

2.07 (1.71–2.97)

2.03 (1.64–2.60)

0.110

HDL-c (mmol/L)

1.14 (0.92–1.44)

1.10 (0.90–1.22)

1.04 (0.88–1.35)

1.20 (0.97–1.36)

0.115

ALT (U/L)

12 (10–18)

14 (10–20)

13 (8–19)

12 (8–19)

0.389

AST (U/L)

18 (16–22)

20 (17–23)

18 (15–22)

20 (15–23)

0.207

hsCRP (mg/L)

1.35 (0.46–5.58)

1.23 (0.58–2.04)

1.47 (0.58–3.34)

1.40 (0.49–3.64)

0.583

PCT (ng/mL)

0.037 (0.024–0.042)

0.037 (0.026–0.045)

0.036 (0.023–0.50)

0.039 (0.030–0.054)

0.088

  1. Data were summarized as the mean ± standard deviation for normally distributed variables or median (interquartile range) for skewed variables continuous variables or as proportion for categorical variables. The Kruskal–Wallis test and ANOVA were used for continuous variables with a skewed or normal distribution, and the chi-square (χ2) test was used for categorical variables. aRoutine exercise: moderate to strenuous intensity ≥3 times a week
  2. Abbreviations: ALT Alanine aminotransferase, AST Aspartate aminotransferase, BMI body mass index, DBP diastolic blood pressure, E2 estradiol, FINS fasting insulin, FPG fasting plasma glucose, FSH follicle-stimulating hormone, HbA1c hemoglobin A1c, HDL-c high-density lipoprotein cholesterol, hsCRP high sensitive C-reactive protein, LDL-c low-density lipoprotein cholesterol, LH luteinizing hormone, MNA-SF Short-form of Mini Nutritional Assessment, PCT procalcitonin, SBP systolic blood pressure, TC total cholesterol, TG triglyceride, TT total testosterone, WC waist circumference
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BMC Geriatrics

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