From: Burden of bloodstream infection in older persons: a population‐based study
Parameter | Age 65–74 N = 783 | 75–84 n = 701 | 84+ n = 370 | P-value |
---|---|---|---|---|
Male | 470 (60.3%) | 410 (50.5%) | 209 (56.5%) | 0.5 |
Hospital-onset Healthcare-associated Community-associated | 139 (17.8%) 377 (48.2%) 267 (34.1%) | 121 (17.3%) 374 (53.4%) 206 (29.4%) | 58 (15.7%) 220 (59.5%) 92 (24.9%) | 0.006 |
Median (interquartile range) Charlson Comorbidity Index | 2 (1–4) | 2 (1–4) | 2 (1–3) | 0.9 |
Co-morbidity Myocardial infarction Congestive heart failure Peripheral vascular disease Stroke Plegia Chronic lung disease Diabetes mellitus Renal disease Liver disease Cancer Dementia Rheumatic disease HIV/AIDS | 88 (11.2%) 65 (8.3%) 76 (9.7%) 59 (7.5%) 26 (3.3%) 163 (20.8%) 239 (30.5%) 90 (11.5%) 73 (9.3%) 229 (29.3%) 29 (3.7%) 58 (6.1%) 1 (0.1%) | 87 (12.4%) 113 (16.1%) 67 (9.6%) 79 (11.3%) 18 (2.6%) 152 (21.7%) 213 (30.4%) 95 (13.6%) 21 (3.0%) 209 (29.8%) 104 (14.8%) 31 (4.4%) 0 | 54 (14.6%) 85 (23.0%) 26 (7.0%) 53 (14.3%) 13 (3.5%) 82 (22.2%) 74 (20.0%) 57 (15.4%) 4 (1.1%) 98 (26.5%) 95 (25.7%) 17 (4.6%) 0 | 0.3 < 0.001 0.3 0.001 0.6 0.8 < 0.001 0.2 < 0.001 0.5 < 0.001 0.3 1 |
Microbiology group Gram-positive Gram-negative Anaerobes Yeast Polymicrobial | 308 (39.3%) 376 (48.0%) 33 (4.2%) 12 (1.5%) 54 (6.9%) | 261 (37.2%) 359 (51.2%) 26 (3.7%) 5 (0.7%) 50 (7.1%) | 114 (30.8%) 213 (57.6%) 15 (4.1%) 2 (0.54%) 26 (7.0%) | 0.1 |
Clinical focus No focus Bone and joint Soft tissue Respiratory Cardiovascular Abdomen/pelvic Central nervous Genitourinary | 121 (15.5%) 60 (7.7%) 76 (9.7) 84 (10.7%) 49 (6.3%) 161 (20.6%) 3 (0.4%) 229 (29.3%) | 107 (15.3%) 37 (5.3%) 54 (7.7%) 74 (10.6%) 45 (6.4%) 147 (21.0%) 1 (0.1%) 236 (33.7%) | 51 (13.8%) 14 (3.8%) 18 (4.9%) 48 (13.0%) 26 (7.0%) 68 (18.4%) 0 145 (39.2%) | 0.016 |
Admitted to hospital | 717 (91.6%) | 645 (92.0%) | 347 (93.8%) | 0.4 |
Median length of stay in days (IQR) All patients Survivors to discharge | 10 (5–24) 9 (5–21) | 9 (4–19) 9 (5–19) | 8 (5–18) 9 (5–20) | 0.1 0.9 |
Day 30 case-fatality | 138 (17.6%) | 167 (23.8%) | 101 (27.3%) | < 0.001 |