Table 2 Diagnostic value of visual rating scale for discriminating dementia of Alzheimer’s type from normal cognition
Scales | Criteria | Age group | Cutoffs | AUC(95%CI) | Sen(%) | Spe(%) | FNR(%) | Youden index | PPV(%) | NPV(%) |
|---|---|---|---|---|---|---|---|---|---|---|
MTAi | – | – | 0.42 (0.32–0.52) | – | – | – | – | – | – | |
PA | – | – | 0.46 (0.36–0.56) | – | – | – | – | – | – | |
GCA | Total | 1 | 0.74 (0.65–0.82) | 63.8 | 73.1 | 36.2 | 0.369 | 49.0 | 80.9 | |
50–64 | 1 | 0.69 (0.54–0.83) | 53.8 | 77.9 | 46.2 | 0.317 | 48.4 | 80.0 | ||
65–74 | 0.5 | 0.74 (0.59–0.88) | 90.5 | 48.1 | 9.5 | 0.386 | 59.1 | 68.9 | ||
75–84 | 1 | 0.69 (0.50–0.88) | 79.2 | 53.8 | 20.8 | 0.33 | 59.7 | 69.2 | ||
MTA | Tian et al’ s criteria | Total | 1.5 | 0.92 (0.89~0.96) | 84.5 | 79.1 | 15.5 | 0.636 | 56.1 | 94.2 |
50–64 | 1.0 | 0.88 (0.78~0.98) | 92.3 | 68.4 | 7.7 | 0.607 | 36.1 | 96.7 | ||
65–74 | 1.5 | 0.95 (0.89~1.00) | 90.4 | 85.2 | 9.6 | 0.756 | 49.8 | 96.7 | ||
75–84 | 2.0 | 0.75 (0.63~0.93) | 70.8 | 82.3 | 29.2 | 0.538 | 42.1 | 90.3 | ||
Scheltens’ criteria | Total | 60.0 | 95.6 | 40.0 | 0.556 | 74.8 | 88.7 | |||
≤ 75 | 2.0 | 70.7 | 95.5 | 29.3 | 0.662 | 63.4 | 91.5 | |||
> 75 | 3.0 | 40.7 | 74.6 | 59.3 | 0.153 | 25.1 | 80.5 |