Event | Definition |
---|---|
Fall/s | New fall/s |
New onset unsteady gait | New onset of unsteady gait that results in poor mobility and unsteady balance |
Acute kidney injury | An increase in serum creatinine by 0.3 mg/dl (26.5 μmol/l) within 48 h or an increase in serum creatinine by 1.5 baseline, which is known or presumed to have occurred within the prior 7 days |
Symptomatic orthostatic hypotension | A systolic blood pressure drop ≥20 mmHg ± diastolic blood pressure drop ≥10 mmHg within 3 min of standing from the lying or sitting posture associated with symptoms |
Major serum electrolyte disturbance | A sodium (Na) of < 130 mmol/l or > 145 mmol/l and/or a potassium (K+) < 3.5 mmol/l or > 5.2 mmol/l and/or a corrected calcium (Ca++) < 2.1 mmol/l or > 2.7 mmol/l |
Symptomatic bradycardia | Heart rate of < 50 beats with symptoms |
New major constipation | Subjective symptoms of hard stools and/or less than 3 bowel movements per week and/or supported by nursing records |
Acute bleeding | Malaena or haematuria or haematemesis or haemoptysis with or without a drop in haemoglobin level > 2 g/dl (not due to rehydration) or associated symptoms (hypotension, tachycardia, pallor) or secondary renal failure |
Acute dyspepsia/nausea/vomiting | Subjective symptoms of acute ‘indigestion’/‘upset stomach’ or acute abdominal pain or acute refusal to eat or acute heartburn/acid reflux or acute nausea/vomiting |
Acute diarrhoea | New liquid stools reported by the patient or the nursing staff or new liquid stools detected by medical staff on physical examination or new liquid (non-solid) stools occurring more than 3 times in 24 h |
Acute delirium | Confirmed by a reliable witness and the DSM-V criteria. Supported by a 4AT ≥ 4 and/or MMSE < 23/30 |
Symptomatic hypoglycaemia | Symptoms with a blood glucose of < 3.5 mmol/L or < 63 mg/dl. |
Unspecified adverse event | For ADEs not specified above e.g. acute liver failure, anaphylaxis |