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Table 3 Relationships between EWGSOP and FNIH-defined sarcopenia with cognitive impairment in a study of British men aged 71–92 years in 2010-12

From: The relationships between body composition characteristics and cognitive functioning in a population-based sample of older British men

 

Normal cognitive ageing (n = 801, 51 %)

Mild cognitive impairment (n = 636, 41 %)

Severe cognitive impairment (n = 133, 8 %)

P value*

Lean mass, grip strength and gait speed cut-offs

 Appendicular Muscle Mass/BMI- FNIH cut-off (<0.789), n(%)

119 (16 %)

131 (23 %)

35 (32 %)

<.001

 Relative Risk Ratio (95 % CI)

1.00

1.57 (1.19–2.09)‡

2.39 (1.51–3.77)‡

 

 Appendicular Muscle Mass/height- EWGSOP cut-off (<=7.23), n(%)

185 (25 %)

137 (24 %)

31 (19 %)

.37

 Relative Risk Ratio (95 % CI)

1.00

0.95 (0.73–1.23)

0.65 (0.39–1.08)

 

 Grip strength- FNIH cut-off (<26 kg), n(%)

190 (25 %)

169 (28 %)

38 (29 %)

.30

 Relative Risk Ratio (95 % CI)

1.00

1.16 (0.90–1.48)

1.20 (0.79–1.83)

 

 Grip strength- EWGSOP cut-off (<30 kg), n(%)

257 (33 %)

234 (38 %)

57 (44 %)

.02

 Relative Risk Ratio (95 % CI)

1.00

1.23 (0.98–1.54)

1.48 (1.01–2.19)†

 

 Gait Speed (<=0.8 m/s), n(%)

187 (24 %)

223 (36 %)

57 (45 %)

<.001

 Relative Risk Ratio (95 % CI)

1.00

1.83 (1.45–2.33)‡

2.60 (1.74–3.87)‡

 

Sarcopenia

 Severe Sarcopenia- EWGSOP definition, n(%)

11 (1.5 %)

15 (2.8 %)

8 (7.5 %)

.001

 Relative Risk Ratio (95 % CI)

1.00

1.78 (0.80–3.95)

4.65 (1.78–12.19)‡

 

 Sarcopenia- FNIH definition, n(%)

13 (1.8 %)

17 (3.2 %)

6 (5.7 %)

.04

 Relative Risk Ratio (95 % CI)

1.00

1.70 (0.81–3.57)

2.90 (1.04–8.05)†

 
  1. EWGSOP European Working Group on Sarcopenia in Older People, FNIH Foundation for the National Institutes of Health Sarcopenia Project
  2. *p-value of respective Chi-Square test
  3. † p < .05
  4. ‡ p < .01
  5. risk ratios are age-adjusted