| Normal cognitive ageing (n = 801, 51 %) | Mild cognitive impairment (n = 636, 41 %) | Severe cognitive impairment (n = 133, 8 %) | P value* |
---|---|---|---|---|
Lean mass, grip strength and gait speed cut-offs | ||||
 Appendicular Muscle Mass/BMI- FNIH cut-off (<0.789), n(%) | 119 (16 %) | 131 (23 %) | 35 (32 %) | <.001 |
 Relative Risk Ratio (95 % CI) | 1.00 | 1.57 (1.19–2.09)‡ | 2.39 (1.51–3.77)‡ |  |
 Appendicular Muscle Mass/height- EWGSOP cut-off (<=7.23), n(%) | 185 (25 %) | 137 (24 %) | 31 (19 %) | .37 |
 Relative Risk Ratio (95 % CI) | 1.00 | 0.95 (0.73–1.23) | 0.65 (0.39–1.08) |  |
 Grip strength- FNIH cut-off (<26 kg), n(%) | 190 (25 %) | 169 (28 %) | 38 (29 %) | .30 |
 Relative Risk Ratio (95 % CI) | 1.00 | 1.16 (0.90–1.48) | 1.20 (0.79–1.83) |  |
 Grip strength- EWGSOP cut-off (<30 kg), n(%) | 257 (33 %) | 234 (38 %) | 57 (44 %) | .02 |
 Relative Risk Ratio (95 % CI) | 1.00 | 1.23 (0.98–1.54) | 1.48 (1.01–2.19)†|  |
 Gait Speed (<=0.8 m/s), n(%) | 187 (24 %) | 223 (36 %) | 57 (45 %) | <.001 |
 Relative Risk Ratio (95 % CI) | 1.00 | 1.83 (1.45–2.33)‡ | 2.60 (1.74–3.87)‡ |  |
Sarcopenia | ||||
 Severe Sarcopenia- EWGSOP definition, n(%) | 11 (1.5 %) | 15 (2.8 %) | 8 (7.5 %) | .001 |
 Relative Risk Ratio (95 % CI) | 1.00 | 1.78 (0.80–3.95) | 4.65 (1.78–12.19)‡ |  |
 Sarcopenia- FNIH definition, n(%) | 13 (1.8 %) | 17 (3.2 %) | 6 (5.7 %) | .04 |
 Relative Risk Ratio (95 % CI) | 1.00 | 1.70 (0.81–3.57) | 2.90 (1.04–8.05)†|  |