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Table 2 Correlates of new antipsychotic drug use among newly admitted residents to LTC and CCC facilities in Ontario, Canada (N = 47,768) – multivariate logistic regression models

From: A retrospective, longitudinal study of factors associated with new antipsychotic medication use among recently admitted long-term care residents

 

Model for women (N = 32,143)

  

Model for men (N = 15,625)

  

New users n = 1,902

New users n = 1,230

Non-users n = 30,241

Non-users n = 14,395

Characteristics

Odds ratio

95 % CI

p value

Odds ratio

95 % CI

p value

Demographic

      

Age (under 75 years)

1.39

(1.19, 1.61)

<0.0001

1.03

(0.88, 1.22)

0.70

Clinical

      

 ADLa score 1–2

1.03

(0.85, 1.25)

0.33

1.08

(0.84, 1.39)

0.21

 ADL score 3+

0.94

(0.78, 1.13)

0.20

0.95

(0.74, 1.22)

0.26

 CPSb score 1–2

1.37

(1.13, 1.66)

0.81

1.47

(1.14, 1.89)

0.74

 CPS score 3+

1.82

(1.48, 2.25)

<0.0001

2.27

(1.74, 2.97)

<0.0001

 Communication CAP

1.05

(0.95, 1.17)

0.34

1.04

(0.91, 1.19)

0.57

 Delirium CAP

1.26

(1.07, 1.47)

0.004

1.20

(0.99, 1.47)

0.07

 Any Dementia

1.89

(1.67, 2.13)

<0.0001

2.23

(1.91, 2.59)

<0.0001

 Congestive Heart Failure

0.90

(0.77, 1.05)

0.19

0.97

(0.80, 1.17)

0.73

 Hypertension

1.03

(0.93, 1.14)

0.55

0.92

(0.81, 1.04)

0.20

 Diabetes (type I and/or II)

0.90

(0.80, 1.02)

0.10

0.93

(0.80, 1.07)

0.32

 Hearing Impairment

1.01

(0.91, 1.11)

0.93

0.83

(0.73, 0.94)

0.004

 Vision Impairment

0.86

(0.78, 0.95)

0.003

0.95

(0.84, 1.08)

0.46

 Painc

0.89

(0.84, 0.95)

0.0007

0.91

(0.83, 0.99)

0.03

 Motor Agitation

1.24

(1.08, 1.44)

0.003

1.45

(1.21, 1.74)

<0.0001

 Delusions

1.60

(1.18, 2.17)

0.002

1.88

(1.21, 2.93)

0.005

 Depressive symptomsd

0.73

(0.64, 0.82)

<0.0001

0.57

(0.47, 0.69)

<0.0001

 Urinary Tract Infection

0.99

(0.83, 1.18)

0.88

0.98

(0.89, 1.08)

0.68

 Number of Medications

0.94

(0.88, 1.01)

0.11

0.95

(0.72, 1.25)

0.70

 Other Psychoactive Medications e

1.68

(1.50, 1.88)

<0.0001

1.66

(1.44, 1.92)

<0.0001

Social

      

 Any Behavioural Problemsf

1.91

(1.71, 2.12)

<0.0001

2.15

(1.88, 2.47)

<0.0001

 Conflict with Staff

1.61

(1.29, 2.01)

<0.0001

0.98

(0.72, 1.34)

0.90

 Conflict with Family/Friends

1.34

(1.10, 1.63)

0.003

1.44

(1.10, 1.87)

0.008

 Reduced Social Engagement

0.78

(0.71, 0.87)

<0.0001

0.94

(0.83, 1.06)

0.32

 Isolation

0.88

(0.68, 1.15)

0.35

1.11

(0.85, 1.46)

0.45

Treatments and Service Use

      

 Use of Restraints

0.84

(0.69, 1.02)

0.07

0.85

(0.67, 1.07)

0.17

 Hospital Stay

1.05

(0.93, 1.19)

0.44

0.87

(0.74, 1.02)

0.09

 Emergency Department Visits

0.98

(0.84, 1.15)

0.79

1.24

(1.02, 1.50)

0.03

Other

      

 Days between Assessments

1.00

(0.99, 1.00)

0.80

1.00

(1.00, 1.00)

0.70

  1. CAP, Clinical Assessment Protocol; CI, confidence interval
  2. aADL: Activities of Daily Living hierarchy scale score – reference = 0
  3. bCPS: Cognitive Performance Scale – reference = 0
  4. cReference = no pain on the Pain Scale
  5. dScore of 3 or higher on the Depression Rating Scale versus score of 0
  6. eIncludes anti-depressants, hypnotics, and anxiolytics
  7. fPresence of any wandering, verbal or physical abuse, resistance to care or socially inappropriate behaviour