Table 2 Multivariable Cox regression analysis for all-cause mortality and hospitalization

Lowest FEV₁/Ht³ quartile

2.13 (1.46-3.09)**

2.13 (1.44-3.14)**

1.77 (1.16-2.70)**

1.69 (1.10-2.60)*

1.68 (1.27-2.21)**

1.73 (1.30-2.31)**

1.56 (1.15-2.11)**

1.65 (1.21-2.25)**

Age

1.08 (1.03-1.13)**

1.07 (1.02-1.12)**

1.06 (1.01-1.11)*

1.04 (1.01-1.08)*

1.04 (1.00-1.07)

1.02 (0.99-1.06)

Male

1.44 (0.98-2.11)

1.08 (0.64-1.81)

0.91 (0.53-1.57)

1.42 (1.09-1.85)*

1.19 (0.82-1.74)

0.99 (0.67-1.47)

Smoker or ex-smoker

1.34 (0.81-2.21)

1.41 (0.86-2.34)

1.40 (0.98-2.00)

1.50 (1.04-2.14)*

History of CVD

1.48 (0.99-2.21)

1.45 (0.96-2.18)

1.46 (1.11-1.91)**

1.37 (1.04-1.82)*

Hypertension

1.61 (1.01-2.55)*

1.53 (0.95-2.48)

1.25 (0.92-1.68)

1.25 (0.92-1.70)

Diabetes

0.72 (0.42-1.21)

0.68 (0.40-1.15)

1.19 (0.86-1.65)

1.09 (0.78-1.52)

Parkinson disease

1.43 (0.35-5.94)

1.76 (0.42-7.35)

0.69 (0.21-2.20)

0.91 (0.28-2.94)

Osteoporosis

1.18 (0.74-1.86)

1.24 (0.77-1.99)

1.51 (1.08-2.09)*

1.55 (1.10-2.17)*

Asthma

1.01 (0.43-2.37)

0.99 (0.42-2.33)

1.50 (0.85-2.65)

1.39 (0.78-2.49)

COPD

1.52 (0.87-2.68)

1.56 (0.87-2.78)

1.08 (0.70-1.65)

1.02 (0.65-1.59)

Anemia

1.53 (0.98-2.38)

1.56 (1.14-2.15)**

hs-CRP > 0.3 mg/dl

1.37 (0.93-2.03)

1.27 (0.96-1.67)

Serum creatinine > 2 mg/dl

1.53 (0.72-3.26)

2.30 (1.32-4.03)**