Potential for alcohol and drug interactions in older adults: evidence from the Irish longitudinal study on ageing

BMC Geriatrics

Table 3 Results of multinomial logistic model of light-moderate, and heavier drinking combined with Alcohol Interactive (AI) medications (N = 2,672)

	Light-Moderate drinker/nondrinker + AI		Heavier drinker/nondrinker + AI
Characteristics	OR (95% CI)	P value	OR (95% CI)	P value
Gender
Male	1.00		1.00
Female	0.75 (0.61 - 0.92)	0.006	0.18 (0.14 - 0.24)	<0.001
Age
60-64	1.00		1.00
65-69	0.80 (0.61 - 1.07)	0.13	0.64 (0.45 - 0.92)	0.02
70-74	0.46 (0.34 - 0.63)	<0.001	0.40 (0.27 - 0.59)	<0.001
75-79	0.50 (0 .36 - 0.69)	<0.001	0.25 (0.16 - 0.39)	<0.001
80+	0.38 (0.27 - 0.54)	<0.001	0.22 (0.13 - 0.35)	<0.001
Residence
Rural	1.00		1.00
Urban	1.48 (1.22 - 1.80)	<0.001	2.36 (1.80 - 3.08)	<0.001
Marital status
Married	1.00		1.00
Never married	0.49 (0.35 - 0.69)	<0.001	0.48 (0 .30 - 0.75)	0.001
Widowed	0.85 (0.66 - 1.10)	0.22	1.12(0.78 - 1.59)	0.54
Divorced/separated	0.57 (0.34 - 0.95)	0.03	0.83 (0.45 - 1.50)	0.53
Education level
None/primary level	1.00		1.00
Secondary level	1.41 (1.13 - 1.76)	0.002	1.91 (1.45 - 2.53)	<0.001
Third level	2.04 (1.60 - 2.61)	<0.001	3.07 (2.23 - 4.24)	<0.001
Self-reported health status
Excellent to very good	1.00		1.00
Good	1.12 (0.89 - 1.39)	0.33	1.12 (0.85 - 1.48)	0.42
Fair to poor	0.84 (0.63 - 1.12)	0.23	0.68 (0.46 - 0.98)	0.04
Depression (CES-D ≥16)	0.96 (0.79 - 1.16)	0.70	0.86 (0.68 - 1.09)	0.21
Smoking history
Never smoked	1.00		1.00
Current smoker	1.09 (0.81 - 1.47)	0.57	2.65 (1.79 – 3.93)	<0.001
Past smoker	1.52 (1.23- 1.89)	<0.001	2.07 (1.53 - 2.78)	<0.001
Number of AI drugs	0.95 (0.90 - 1.00)	0.09	0.91 (0.85 - 0.98)	0.018
Number of co-morbidities	1.04 (0.94 - 1.15)	0.49	1.29 (1.12 - 1.47)	<0.001

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