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Fig. 3 | BMC Geriatrics

Fig. 3

From: No effect of 25-hydroxyvitamin D supplementation on the skeletal muscle transcriptome in vitamin D deficient frail older adults

Fig. 3

Minimal effect of calcifediol and placebo on skeletal muscle gene expression in vitamin D deficient frail older adults. Top left (a): P-values for the change in gene expression for all genes after filtering; before and after calcifediol supplementation. Uniform distribution (i.e. no increased frequency of genes for lower p-values) indicates an absence of an effect. Top right (b): values for the change in gene expression; before and after in the placebo group. Bottom left (c): P-values for the interaction effect (change in the calcifediol group vs. change in placebo group). Bottom right (d): receiver operator characteristic curve for the PLS-DA model

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