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Table 5 Association between deprived and unequal neighborhood characteristics and risk of dementia only in women

From: Influence of activity space on the association between neighborhood characteristics and dementia risk: results from the 3-City study cohort

Deprived and unequal neighborhood characteristics

All-type dementia (n = 517)

Univariate model

Multivariate modela

n

HR (95% IC)

p

HR (95% IC)

p

3C deprivation score

No limited activity space

     

T1 (most privileged)

110

1

1

T2

120

1.03 (0.78–1.35)

0.85

1.01 (0.79–1.30)

0.91

T3 (most deprived)

151

1.24 (0.97–1.60)

0.09

1.25 (0.98–1.60)

0.08

Limited activity space

     

T1 (most privileged)

36

1

1

T2

40

1.07 (0.68–1.73)

0.68

1.08 (0.68–1.70)

0.76

T3 (most deprived)

60

1.49 (0.96–2.30)

0.08

1.39 (0.89–2.16)

0.15

Proportion of blue collar workers

No limited activity space

     

T1 (< 13.6)

135

1

1

T2 (13.6–20.8)

119

0.98 (0.74–1.29)

0.87

0.87 (0.68–1.10)

0.24

T3 (> 20.8)

127

1.06 (0.83–1.36)

0.63

0.87 (0.69–1.09)

0.23

Limited activity space

     

T1 (< 13.6)

42

1

1

T2 (13.6–20.8)

39

0.92 (0.62–1.38)

0.68

0.93 (0.61–1.40)

0.72

T3 (> 20.8)

55

1.21 (0.84–1.74)

0.32

1.11 (0.78–1.60)

0.56

Proportion of households without car

No limited activity space

     

T1 (< 21.2)

110

1

1

T2 (21.2–29.0)

137

1.14 (0.89–1.46)

0.30

1.19 (0.96–1.49)

0.12

T3 (> 29.0)

134

1.10 (0.84–1.46)

0.49

1.11 (0.86–1.44)

0.43

Limited activity space

     

T1 (< 21.2)

34

1

1

T2 (21.2–29.0)

41

1.20 (0.75–1.91)

0.46

1.29 (0.82–2.02)

0.27

T3 (> 29.0)

61

1.43 (0.91–2.25)

0.12

1.46 (0.94–2.26)

0.09

Gini index

No limited activity space

     

T1 (< 0.31)

113

1

1

T2 (0.31–0.35)

133

1.09 (0.84–1.41)

0.53

1.10 (0.87–1.41)

0.43

T3 (> 0.35)

135

1.04 (0.80–1.35)

0.80

1.14 (0.89–1.45)

0.30

Limited activity space

     

T1 (< 0.31)

39

1

1

T2 (0.31–0.35)

47

1.25 (0.78–2.00)

0.35

1.32 (0.86–2.04)

0.22

T3 (> 0.35)

50

1.36 (0.86–2.16)

0.19

1.28 (0.82–2.01)

0.28

  1. aMarginal Cox model adjusted for study center, education level, income, occupational category, APOEε4 carrier status, diabetes, history of cardiovascular diseases, depressive symptoms and disability (IADL « budget, medication, phone »)
  2. Note: People with limited activity space = people who have need to help to go shopping, or if they are unable to move without being accompanied, or if people are confined at home or at their neighborhood