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Table 3 Associations between the factors influencing patient HRQoL and the 13 items of the QoL-AD

From: Factors associated with quality of life in patients with Alzheimer’s disease

 

Patient

Caregiver

 

Depression

Polypharmacy

Anxiety (NPI)

Depression

Polypharmacy

Caregiver burden

Physical health

 

*

 

*

*

 

Energy

   

*

 

*

Mood

*

 

*

*

*

*

Living situation

      

Memory

*

 

*

  

*

Family

     

*

Marriage

     

*

Friends

     

*

Self as a whole

  

*

*

  

Ability to do chores

     

*

Ability to do things for fun

*

  

*

*

*

Financial situation

      

Life as a whole

*

  

*

 

*

  1. *p < 0.05 (Cochrane Armitage test for trend). For all significant tests, a decrease in the rate of the associated factor (depression, polypharmacy, anxiety or caregiver burden) was observed across the spectrum of responses of the QoL-AD (i.e. from response 1 (poor HRQoL) to item response 4 (excellent HRQoL))
  2. For example, for the item “mood” of the patient QoL-AD, the proportion of patients with depression was 67% for response “1”, 29% for response “2”, 10% for response “3” and 0% for response “4” (p = 0.0002)
  3. Polypharmacy: > 3 medications per day;
  4. NPI NeuroPsychiatric Inventory
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BMC Geriatrics

ISSN: 1471-2318

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