Exploration of 27 plasma immune markers: a cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons

Table 3 The receiver operating characteristic curve analyses of plasma immune markers

Immune markers	AUC ^a CI (95%)	Sensitivity	Specificity
IL-1β	0.97 (0.93; 1.00)	0.94	0.95
IL-1ra	0.86 (0.74; 0.99)	0.89	0.85
IL-2	0.84 (0.72; 0.96)	0.81	0.75
IL-4	0.78 (0.68; 0.87)	0.63	0.90
IL-5	0.80 (0.70; 0.90)	0.81	0.75
IL-6	0.86 (0.72; 1.00)	0.94	0.80
IL-7	0.94 (0.85; 1.00)	0.94	0.90
IL-8	0.93 (0.86; 0.99)	0.84	0.85
IL-9	0.86 (0.74; 0.98)	0.83	0.70
IL-10	0.52 (0.38; 066)	0.44	0.65
IL-12	0.84 (0.70; 0.97)	0.92	0.75
IL-13	0.81 (0.69; 0.92)	0.70	0.90
IL-15	0.81 (0.74; 0.88)	0.63	1.00
IL-17	0.89 (0.79; 1.00)	0.94	0.85
Eotaxin	0.88 (0.79; 0.97)	0.80	0.80
bFGF	0.86 (0.77; 0.96)	1.00	0.60
GCSF	0.93 (0.85; 1.00)	0.98	0.75
GMCSF	0.86 (0.78; 0.95)	0.56	1.00
IFN-γ	0.71 (0.58; 0.83)	0.59	0.80
IP-10	0.69 (0.56; 0.83)	0.02	1.00
MCP-1	0.90 (0.84; 0.97)	0.81	0.90
MIP-1α	0.72 (0.58; 0.87)	0.98	0.45
MIP-1β	0.75 (0.60; 0.89)	0.78	0.65
PDGFBB	0.83 (0.70; 0.96)	0.86	0.75
RANTES	0.71 (0.58; 0.84)	0.64	0.75
TNF	0.88 (0.80; 0.96)	0.75	0.90
VEGF	0.98 (0.95; 1.00)	0.92	0.95

Abbreviations: AUC area under curve, bFGF basic fibroblast growth factor, CI confidence interval, G-CSF granulocyte-colony stimulating factor, GM-CSF granulocyte macrophage colony stimulating factor, IFN interferon, IL interleukin, IP-10 interferon-inducible protein, MCP-1 monocyte chemotactic protein, MIP macrophage inflammatory protein, PDGF-BB platelet derived growth factor-BB, RANTES regulated upon activation T cell expressed and secreted, TNF tumour necrosis factor, VEGF vascular endothelial growth factor
^a AUC: Area under the receiver operating characteristic (ROC) curve

ISSN: 1471-2318