Preoperative medication use and postoperative delirium: a systematic review

Kassie, Gizat M.; Nguyen, Tuan A.; Kalisch Ellett, Lisa M.; Pratt, Nicole L.; Roughead, Elizabeth E.

doi:10.1186/s12877-017-0695-x

BMC Geriatrics

Table 1 Characteristics of studies included in the systematic review by type of surgery

From: Preoperative medication use and postoperative delirium: a systematic review

Study (First Author, Publication year, Country)	Year of data collection	No of study participants	Age, Mean (SD)	Sex, Male (%)	Type of surgery	Diagnostic tool	Delirium incidence (%)	Study quality (star)^a
Juliebo, 2009, Norway [35]	2005–2006	187	84.0^b (79–88)^c	24	Orthopaedic	CAM	36	7
Kudoh, 2004, Japan [30]	NR	328	73.2	2	Orthopaedic	CAM	15	7
Muangpaisan, 2015, Thailand [43]	2010–2012	80	79.4 (7.9)	25	Hip fracture	CAM	45	7
Goldenberg, 2006, USA [25]	2000–2002	77	81.9 (7.5)	35	Hip fracture	CAM	48	7
Galanakis, 2001, Germany [18]	1998	105	74.9^b (60–98)^d	29	Hip surgery	CAM	24	9
Duppils, 1999, Sweden [29]	1996–1997	225	85.4	33	Hip surgery	DSM-IV	20	6
Schuurmans, 2003, Netherlands [31]	1998–1999	92	82.7 (6.7)	13	Hip fracture	DSM-IV	20	7
Huang, 2017, Singapore [16]	2006	954	78^be, 67 ^bf	81	Total knee arthroplasty	DSM-IV	1	7
Mariscalco, 2012, Italy [36]	2004–2010	4659	67.8 (9.2)	79	Coronary revascularization	CAM-ICU	3	9
Afonso, 2010, USA [41]	2008	112	66 (19–84)^d	57	Cardiac and thoracic aortic	CAM-ICU	34	7
Burkhart, 2010, Switzerland [17]	NR	113	74.3 (5.5)	68	Cardiopulmonary bypass	CAM	30	7
Santos, 2004, Brazil [38]	1996–1999	220	70.7	65	Coronary artery bypass graft	CAM-ICU	34	8
Rudolph, 2008, USA [39]	NR	42	68.1	83	Cardiac	CAM	29	8
Tan, 2008, USA [32]	2006	53	62.7	100	Cardiac	MDAS	23	6
Veliz-Reissmuller, 2007, Sweden [44]	NR	107	72.9 (5.4)	62	Elective cardiac	CAM	23	7
Katznelson, 2009b, Canada [34]	2006–2007	582	67.9	71	Elective and emergency vascular	NEECHAM	22	9
Van Der Mast, 1999, Netherlands [40]	NR	296	63.0 (11)	65	Elective cardiac	DSM-III-R	14	7
Katznelson, 2009c, Canada [37]	2005–2006	1059	63.6^g	71	Cardiopulmonary bypass	CAM-ICU	12	9
Tully, 2010, Australia [27]	2007–2009	158	64.7 (10.6)	79	Coronary artery bypass graft	DSI	31	8
Benoit, 2005, Canada [8]	2000–2003	102	70.8 (8.2)	77	Elective abdominal aortic aneurysm	CAM	33	7
Tognoni, 2011, Italy [45]	NR	90	74.3 (0.40)	90	Urologic	CAM	9	7
Dai, 2000, Taiwan [26]	1995–1997	701	72.7 (6.3)	46	Elective orthopaedic and urologic	DSM-IV	5	7
Chen, 2015, Taiwan [14]	2009–2013	401	61.2 (11.2)	74	Hepatectomy for HCC	CAM	8	7
Jeong, 2016, Korea [15]	2014–2015	475	76.0^b(65–96)^d	45	Cancer surgery	DSM-IV	4	8
Brouquet, 2010, France [42]	2006–2008	118	81.3 (4.8)	48	Elective major abdominal	CAM	24	8
Behrends, 2013, USA [33]	2003–2011	472	38.1^h	52	Major non-cardiac	CAM	29	7
Litaker, 2001, USA [28]	NR	500	67.0 (9.0)	NR	Elective major surgery	CAM	11	8
Xue, 2016, China [20]	2010–2015	358	75.1	NR	Transurethral resection of prostate	CAM	8	8
Brown, 2016, USA [19]	2012–2014	89	74^b	53	Spine surgery	CAM/CAM-ICU	41	9

NR not reported, SD standard deviation, DSI delirium symptom interview, DSM diagnostic and statistical manual for mental disorders, DOS delirium observation screening, MDAS memorial delirium assessment scale, NEECHAM neelon and champagne confusion scale, HCC Hepatocellular carcinoma
^aStudy quality assessment as per NOS; ^bMedian; ^cInterquartile range; ^dRange; ^edelirium group; ^fnon-delirium group; ^g63.6% were > 60 years old; ^h38.1% were > 75 years

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