Table 1 Characteristics of 164 elderly patients with hip fracture
Characteristics | Intervention N = 32 | Usual care N = 132 | P-value |
|---|---|---|---|
Patient characteristics | |||
Age, mean ± SD | 83.8 ± 6.2 | 85.1 ± 6.7 | 0.28 |
Men, n (%) | 7 (21.9) | 28 (21.2) | 1.00 |
Institutional resident, n (%) | 7 (21.9) | 47 (35.6) | 0.15 |
CCI, mean ± SD | 2.7 ± 1.6 | 2.0 ± 1.8 | 0.04 |
Number of medications at admission | |||
Total, mean ± SD | 9.2 ± 2.5 | 7.8 ± 2.5 | 0.01 |
5–8 medications, n (%) | 15 (46.9) | 88 (66.7) | 0.04 |
9–12 medications, n (%) | 13 (40.6) | 38 (28.8) | 0.21 |
13 or more medications, n (%) | 4 (12.5) | 6 (4.5) | 0.11 |
Number of medications at discharge | |||
Total, mean ± SD | 4.5 ± 2.6 | 6.8 ± 2.4 | < 0.001 |
0–4 medications, n (%) | 18 (56.3) | 21 (15.9) | < 0.001 |
5–8 medications, n (%) | 13 (40.6) | 85 (64.4) | 0.02 |
9–12 medications, n (%) | 0 (0.0) | 23 (17.4) | 0.02 |
13 or more medications, n (%) | 1 (3.1) | 3 (2.3) | 1.00 |
Fall-risk-increasing drugsa at admission | |||
Total number, mean ± SD | 2.9 ± 1.3 | 2.6 ± 1.4 | 0.22 |
0–2 medications, n (%) | 13 (40.6) | 62 (47.0) | 0.56 |
3–5 medications, n (%) | 16 (50.0) | 65 (49.2) | 1.00 |
6 or more medications, n (%) | 1 (3.1) | 5 (3.8) | 1.00 |
Fall-risk-increasing drugsa at discharge | |||
Total number, mean ± SD | 1.4 ± 1.2 | 2.1 ± 1.4 | 0.01 |
0–2 medications, n (%) | 27 (84.4) | 80 (60.6) | 0.01 |
3–5 medications, n (%) | 5 (15.6) | 50 (37.9) | 0.02 |
6 or more medications, n (%) | 0 (0.0) | 2 (1.5) | 1.00 |
PIMsb at admission | |||
Total number, mean ± SD | 1.5 ± 0.8 | 1.3 ± 1.1 | 0.19 |
0–1 medication, n (%) | 17 (53.1) | 83 (62.9) | 0.32 |
2–3 medications, n (%) | 15 (46.9) | 44 (33.3) | 0.22 |
4 or more medications, n (%) | 0 (0.0) | 5 (3.8) | 0.58 |
PIMsb at discharge | |||
Total number, mean ± SD | 0.8 ± 0.8 | 1.1 ± 1.0 | 0.03 |
0–1 medication, n (%) | 27 (84.4) | 89 (67.4) | 0.08 |
2–3 medications, n (%) | 5 (15.6) | 41 (31.1) | 0.12 |
4 or more medications, n (%) | 0 (0.0) | 2 (1.5) | 1.00 |
Past medical history, n (%) | |||
Dementia | 14 (43.8) | 55 (41.7) | 0.84 |
Heart diseasec | 5 (15.6) | 28 (21.2) | 0.63 |
Stroke | 11 (34.4) | 28 (21.2) | 0.16 |
Diabetes mellitus | 6 (18.6) | 35 (26.5) | 0.50 |
Hip fracture | 2 (6.3) | 19 (14.4) | 0.37 |
Any fracture | 14 (43.8) | 44 (33.3) | 0.31 |
Current smoker, n (%) | 1 (3.1) | 11 (8.3) | 0.46 |
Current drinker, n (%) | 3 (9.4) | 10 (7.6) | 0.72 |
Type of hip fracture, n (%) | |||
Intracapsular fracture | 17 (53.1) | 60 (45.5) | 0.55 |
Intertrochanteric fracture | 11 (36.7) | 67 (50.8) | 0.12 |
Subtrochanteric fracture | 4 (12.5) | 4 (3.0) | 0.05 |
Others | 0 (0.0) | 1 (0.8) | 1.00 |
Management during admission | |||
Surgery, n (%) | 31 (96.9) | 129 (97.7) | 0.58 |
VTE prophylaxis, n (%) | 32 (100) | 130 (98.5) | 1.00 |
Perioperative antibiotics, n (%) | 31 (100) | 129 (100) | 1.00 |
Medical consultationd, n (%) | 7 (21.9) | 41 (31.7) | 0.39 |
Osteoporosis treatment, n (%) | |||
PTH analogue | 2 (6.3) | 2 (1.5) | 0.17 |
Bisphosphonate | 3 (9.4) | 6 (4.5) | 0.38 |
Vitamin D | 3 (9.4) | 21 (15.9) | 0.42 |