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Table 3 Numerical definitions of polypharmacy and associated terms by duration of therapy/ healthcare setting

From: What is polypharmacy? A systematic review of definitions

Term

Number of medications

Number of studies

References

Polypharmacy

≥ 2 for > 240 days (long term)

1

[101]

 

≥ 5 medications in the same month

1

[103]

 

> 5 medications for ≥ 90 days

1

[104]

 

≥ 5 medications in the same quarter of a year

1

[105]

 

≥ 5 medicines at hospital discharge

1

[106]

 

5 to 9 medicines on the day of maximum number of prescriptions of the study year (on the day of the study year when the number of medications prescribed was highest)

1

[107]

 

5 to 9 medications for ≥ 90 days

1

[108]

 

5 to 9 medicines during hospital stay

1

[109]

 

≥ 10 medicines during hospital stay

1

[110]

Major polypharmacy

≥ 10 on the day of maximum number of prescriptions of the study year (on the day of the study year when the number of medications prescribed was highest)

1

[107]

Hyperpolypharmacy

≥ 10 medications for ≥90 days

1

[108]

Excessive polypharmacy

≥ 10 medications in the same quarter of a year

1

[105]

 

≥ 10 medications during hospital stay

1

[109]

Persistent polypharmacy

≥ 5 medications for 181 days

1

[52]

Chronic polypharmacy

≥ 5 medications in 1 month for 6 months (consecutive or not) in a year

1

[111]