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Table 2 Prevalence and persistence of PTD use according to the presence of dementia at each assessment (%)

From: Persistent use of psychotropic drugs in nursing home residents in Norway

  Prevalence in percentages
A1 A2 A3 A4 A5
All (n = 1163) D/nD (n = 932/227) All (n = 789) D/nD (n = 628/159) All (n = 395) D/nD (n = 300/94) All (n = 209) D/nD (n = 160/48) All (n = 98) D/nD (n = 75/22)
Antipsychotics (AP) 24.1 26.0/15.9*** 25.2 26.4/20.8 20.5 22.0/16.0 20.6 22.5/14.6 20.4 20.0/22.7
 Trad. AP 11.3 11.5/11.0 12.2 11.6/14.5 9.4 9.0/10.6 8.6 9.4/6.3 12.2 12.0/13.6
 Atypical AP 13.2 14.9/5.7*** 13.8 15.6/6.9*** 11.9 13.7/6.4** 12.6 13.1/8.3 8.2 8.0/9.1
Antidepressants 38.3 39.1/34.8 37.3 37.9/34.0 36.7 35.3/40.4 35.4 33.1/41.7 32.7 29.3/40.9
Anxiolytics 24.2 23.8/26.4 24.2 22.9/29.6* 25.1 21.3/37.2*** 28.7 26.9/35.4 22.4 21.3/27.3
Sedatives 29.0 26.4/39.6*** 26.6 23.4/38.4*** 24.1 21.0/33.0* 23.9 19.4/37.5** 23.5 20.0/31.8
Antidementia drug 11.3 13.5/2.2*** 9.8 11.8/1.9*** 5.3 6.3/2.1* 2.9 3.1/2.1 0 0/0
Any PTD 72.9 74.5/66.5* 71.4 71.5/70.4 70.4 67.7/78.7* 69.4 66.9/77.1 63.3 57.3/81.8**
  Persistence at two consecutive time points in percentages
  A1–A2 A2–A3 A3–A4 A4–A5
   All D/nD All D/nD All D/nD All D/nD
Antipsychotics (AP)    76.7 75.2/88.9* 64.9 67.6/55.0 69.6 67.5/83.3 70.0 68.8/75.0
 Trad. AP    73.6 70.8/84.2 61.4 63.3/57.1 73.7 73.3/75.0 80.0 75.0/100
 Atypical AP    74.5 74.7/80.0 61.5 63.0/50.0 62.1 59.3/100*** 60.0 62.5/50.0
Antidepressants    80.4 79.8/82.8 76.5 73.1/87.9* 72.2 66.1/89.5** 75.7 76.9/70.0
Anxiolytics    76.9 73.6/89.5** 69.2 62.7/84.4** 86.8 82.1/100** 66.7 66.7/66.7
Sedatives    70.9 65.8/82.8** 64.8 69.1/55.6 69.6 64.9/77.8 68.0 58.8/85.7
Antidementia drug    66.0 65.3/100*** 38.1 36.6/100*** 27.3 27.3/0 0 0/0
Any PTD    89.8 88.7/94.3* 85.3 82.4/94.2** 89.3 86.6/97.3** 78.4 75.5/85.0
  1. A1–A5: Assessment 1–5
  2. D Dementia CDR ≥ 1; nD No dementia CDR < 1
  3. CDR ratings were missing for 4 people at A1, 2 people at A2 and 2 people at A3
  4. CDR Clinical Dementia Rating scale
  5. Trad Conventional
  6. PTD Psychotropic drugs
  7. *p < 0.05, **p ≤ 0.01; ***p ≤ 0.001 (Z-test for proportions used)