Potential unfavorable impacts of BDNF Val66Met polymorphisms on metabolic risks in average population in a longevous area

Peng, Jun-Hua; Liu, Cheng-Wu; Pan, Shang-Ling; Wu, Hua-Yu; Liang, Qing-Hua; Gan, Rui-Jing; Huang, Ling; Ding, Yi; Bian, Zhang-Ya; Huang, Hao; Lv, Ze-Ping; Zhou, Xiao-Ling; Yin, Rui-Xing

doi:10.1186/s12877-016-0393-0

Table 2 Correlation between parameters and the BDNF Val66Met polymorphism

From: Potential unfavorable impacts of BDNF Val66Met polymorphisms on metabolic risks in average population in a longevous area

Parameter	Relative factor	Unstandardized coefficients	Standard error	Standardized coefficients	t	P
LG
BMI	WC	0.118	0.020	0.296	5.924	0.000
	HC	0.184	0.025	0.342	7.333	0.000
	DBP	−0.498	0.227	−0.072	−2.193	0.029
FBG	Sex	0.353	0.106	0.147	3.326	0.001
	TG	0.391	0.122	0.143	3.217	0.001
	WC	0.012	0.006	0.093	2.094	0.037
SBP	Sex	4.815	2.401	0.091	2.005	0.045
DBP	TC	1.879	0.586	0.143	3.208	0.001
	BMI	0.484	0.162	0.133	2.995	0.003
PP	-	-	-	-	-	-
TC	DBP	0.011	0.003	0.139	3.146	0.002
	Sex	0.223	0.091	0.110	2.445	0.015
	FBG	0.088	0.038	0.103	2.306	0.022
	Genotype	−0.132	0.063	−0.093	−2.090	0.037
TG	FBG	0.058	0.016	0.159	3.556	0.000
	DBP	0.004	0.001	0.108	2.425	0.016
HDL-C	BMI	−0.015	0.007	−0.105	−2.336	0.020
LDL-C	DBP	0.009	0.003	0.131	2.930	0.004
	Sex	0.230	0.079	0.131	2.921	0.004
OG
BMI	WC	0.090	0.037	0.054	2.427	0.016
	Sex	0.730	0.144	0.121	5.062	0.000
	DBP	0.040	0.006	0.148	6.502	0.000
	Age	0.171	0.067	0.059	2.554	0.011
FBG	WC	−0.041	0.011	−0.173	−3.691	0.000
	DBP	−0.649	0.131	−0.205	−4.952	0.000
SBP	Age	0.902	0.096	0.356	9.377	0.000
	BMI	1.522	0.290	0.199	5.251	0.000
	Sex	−4.215	1.751	−0.091	−2.407	0.016
DBP	BMI	1.669	0.172	0.447	9.717	0.000
	Sex	−4.944	0.838	−0.219	−5.897	0.000
	HC	−0.924	0.421	−0.085	−2.197	0.028
	FBG	−0.651	0.235	−0.105	−2.767	0.006
PP	Age	0.859	0.083	0.393	10.389	0.000
TC	WC	−0.037	0.013	−0.213	−2.911	0.004
	Age	−0.013	0.005	−0.105	−2.670	0.008
	BMI	0.069	0.027	0.182	2.588	0.010
	DBP	−0.008	0.004	−0.084	−2.065	0.039
TG	WC	0.057	0.011	0.353	5.282	0.000
	Sex	−0.076	0.033	−0.151	−2.287	0.023
HDL-C	WC	−0.012	0.002	−0.189	−4.676	0.000
	Sex	0.115	0.045	0.100	2.543	0.011
LDL-C	BMI	0.113	0.014	0.328	7.871	0.000
	DBP	−0.012	0.004	−0.125	−2.996	0.003
CG
BMI	WC	0.151	0.025	0.278	5.998	0.000
	Age	0.247	0.079	0.084	3.123	0.002
FBG	WC	0.186	0.055	0.137	3.359	0.001
SBP	Age	−4.021	1.801	−0.086	−2.232	0.026
	HC	0.706	0.152	0.181	4.631	0.000
DBP	Sex	0.541	0.142	0.157	3.822	0.000
	FBG	−0.650	0.305	−0.087	−2.133	0.033
PP	Age	−3.783	1.391	−0.104	−2.720	0.007
	HC	0.429	0.114	0.141	3.751	0.000
	Sex	4.185	1.404	0.113	2.980	0.003
TC	BMI	0.045	0.020	0.149	2.310	0.021
	Age	−0.015	0.004	−0.143	−3.320	0.001
	CC	−0.040	0.011	−0.275	−3.737	0.000
	WC	0.026	0.008	0.243	3.117	0.002
TG	BMI	0.076	0.021	0.223	3.586	0.000
	Age	−0.027	0.005	−0.233	−5.740	0.000
	FBG	0.096	0.029	0.131	3.270	0.001
	HC	−0.058	0.013	−0.315	−4.616	0.000
	WC	0.029	0.009	0.246	3.365	0.001
HDL-C	Sex	−0.003	0.001	−0.108	−2.688	0.007
	WC	−0.008	0.002	−0.154	−3.827	0.000
LDL-C	WC	0.012	0.004	0.120	2.914	0.004

Abbreviations: LG long-lived group, OG offspring group, CG control group, WC waist circumference, HC hip circumference, CC chest circumference, BMI body mass index, FPG fasting plasma glucose, SBP systolic blood pressure, DBP diastolic blood pressure, PP pulse pressure, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol

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ISSN: 1471-2318

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