Table 2 Quality of overall evidence for each environmental factor

 Nitrogen oxides (NO_x)

2

Strong

↑

 Carbon monoxide (CO)

1

Moderate

↑

 Environmental tobacco smoke

1

Moderate

↑

 Particulate matter (PM₁₀&_2.5)

1

1

Strong

↑

 Ozone (O₃)

1

1

Strong

↑

 Arsenic

2

Moderate

↕

 Lead

1

Weak

↑

 Aluminium

1

15

Moderate

↕

 Calcium

1

Weak

–

 Cobalt

1

Weak

–

 Copper

2

1

Weak

↕

 Iron

2

1

Weak

↕

 Manganese

1

Weak

↑

 Molybdenum

1

Weak

–

 Nickel

1

Weak

–

 Uranium

1

Weak

–

 Zinc

2

Weak

↕

 Fluoride

1

Weak

↑

 Selenium

1

Moderate

↕

 Silicon (and silica)

2

2

Strong

↕

 Aluminium

(occupational exposure)

1

3

Weak

↕

 Defoliants/fumigants

1

Weak

↑

 Diesel motor exhaust

1

Moderate

–

 Electromagnetic fields

1

Moderate

↕

 Excessive noise

1

Weak

↓

 Glues/adhesives

1

1

Weak

↕

 Pesticides/fertilizers/herbicides/insecticides

5

2

2

Strong

↕

 Lead (occupational exposure)

1

Weak

–

 Metals (occupational exposure)

1

Moderate

↑

 Inks/dyes

1

Weak

–

 Paints/stains/varnishes

1

Weak

–

 Gasoline/fuels/oils

1

Weak

–

 Solvents/degreasers

2

1

1

Strong

↕

 Liquid plastics/rubbers

1

Weak

–

 Vibratory tools

1

Weak

–

 Radiation

1

Weak

↑

 Climate

1

Weak

–

 Electric and magnetic fields

1

2

Moderate

↕

 Mobile phone use

1

Weak

↓

 Vitamin D

3

1

Strong

↑

 Water pH

1

Weak

↑