Loss of health related quality of life following low-trauma fractures in the elderly

Tarride, Jean-Eric; Burke, Natasha; Leslie, William D.; Morin, Suzanne N.; Adachi, Jonathan D.; Papaioannou, Alexandra; Bessette, Louis; Brown, Jacques P.; Pericleous, Louisa; Muratov, Sergei; Hopkins, Robert B.

doi:10.1186/s12877-016-0259-5

BMC Geriatrics

Table 4 Regression analysis to explain change in HUI-2 utility score (36-month post fracture minus pre-fracture)

From: Loss of health related quality of life following low-trauma fractures in the elderly

	HC and LTC combined		HC		LTC		With neurological conditions (HC and LTC)		Without neurological conditions (HC and LTC)
	Coefficient (SE)	p-value	Coefficient (SE)	p-value	Coefficient (SE)	p-value	Coefficient (SE)	p-value	Coefficient (SE)	p-value
Intercept*	−0.098 (0.005)	<0.001	−0.098 (0.005)	<0.001	−0.103 (0.018)	<0.001	−0.165 (0.011)	<0.001	−0.100 (0.005)	<0.001
Age (years >80)	−0.002 (0.000)	<0.001	−0.002 (0.000)	<0.001	−0.001 (0.000)	0.004	−0.002 (0.000)	0.000	−0.002 (0.000)	<0.001
Men (vs women)	−0.011 (0.006)	0.084	−0.006 (0.008)	0.472	−0.019 (0.009)	0.042	−0.015 (0.009)	0.094	−0.006 (0.009)	0.465
Hip (vs non-hip)	−0.007 (0.006)	0.233	−0.004 (0.008)	0.632	−0.011 (0.007)	0.131	−0.020 (0.007)	0.007	0.006 (0.008)	0.493
Long term care (vs home care)	0.040 (0.009)	<0.001	–	–	–	–	0.057 (0.010)	<0.001	−0.006 (0.018)	0.736
Endocrine/metabolism condition	−0.003 (0.006)	0.578	−0.005 (0.009)	0.609	−0.001 (0.007)	0.835	−0.002 (0.008)	0.782	−0.006 (0.010)	0.559
Heart/circulation condition	0.008 (0.006)	0.159	0.013 (0.008)	0.110	0.004 (0.009)	0.636	0.009 (0.008)	0.246	0.010 (0.009)	0.249
Musculoskeletal condition	0.019 (0.006)	<0.002	0.021 (0.007)	0.005	0.017 (0.011)	0.123	0.018 (0.010)	0.056	0.021 (0.008)	0.007
Neurological condition	−0.056 (0.007)	<0.001	−0.073 (0.009)	<0.001	−0.007 (0.011)	0.532	–	–	–	–
Psychiatric/mood condition	−0.000 (0.007)	0.919	0.000 (0.011)	0.998	0.001 (0.007)	0.914	0.003 (0.008)	0.724	−0.005 (0.012)	0.663
Pulmonary condition	−0.001 (0.007)	0.934	−0.003 (0.011)	0.774	0.005 (0.009)	0.558	0.003 (0.010)	0.723	−0.002 (0.011)	0.825
Sensory condition	0.009 (0.007)	0.184	−0.001 (0.011)	0.952	0.015 (0.007)	0.040	0.012 (0.008)	0.147	0.006 (0.012)	0.597
Other condition	−0.010 (0.008)	0.156	−0.011 (0.011)	0.337	−0.010 (0.008)	0.224	−0.013 (0.009)	0.131	−0.006 (0.012)	0.620

*Intercept reflects change in HRQoL for age 80 women, and where covariates are set to zero: i.e., non-hip fracture, in home care, without comorbid conditions
For example, the mean change in HRQoL for a group of men aged 85 years in LTC for hip fractures with heart/circulation conditions would be (−0.098) + (−0.002) ∗ 5 + (−0.011) + (−0.007) + (0.040) + (0.008) = − 0.078
HUI-2 Health Utility Index Version 2

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