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Table 4 Overview of studies that defined study participants with dementia based on a recorded diagnosis and additional cognitive screenings

From: People with dementia in nursing home research: a methodological review of the definition and identification of the study population

Publications

Method of sample determination

Definition and criteria used for (existing) dementia diagnostics

Screenings performed to define and describe dementia

Qualification and training of professionals involved

[48]

Residents with dementia were identified using a mixed stepwise approach:

1st step: Multiple combined inclusion criteria:

â–ª Presence of dementia diagnosis in the nursing and medical records and

▪ MMSE ≤ 24

2nd step: In case of incongruity of diagnosis and MMSE result, dementia diagnostics were performed, diagnostics were also performed for residents with a suspected dementia but no diagnosis

▪ Exclusion criteria: Presence of other neurological/psychiatric diseases that could explain patients’ decline in cognitive function (schizophrenia, bipolar disorders, mental retardation)

â–ª Existing dementia diagnosis performed in 70 % by GPs and 30 % by medical specialists and according to ICD-10 criteria

â–ª An ICD-10/DSM-IV conform study diagnosis was assessed based on clinical investigation and MMSE

â–ª Dementia severity stages: MMSE: 0-9 severe/very severe; 10-18 moderate; 19-24 = mild dementia

MMSE, FAST, AES, NPI

Diagnosis: Physician from the research team who was experienced in geriatric psychiatry

Screening instruments: Specifically trained raters, including medical students with an advanced academic degree and physicians experienced in geriatric psychiatry

[49]

[50]a

[51]

[81]b

[76]

Residents with dementia were identified using two combined inclusion criteria:

â–ª Confirmed presence of primary degenerative dementia and

â–ª MMSE < 24

▪ Exclusion criteria: presence of other neurological/psychiatric diseases that could explain patients’ decline in cognitive function (such as addiction, major depression, or schizophrenia), high nursing care needs, blindness, deafness

â–ª Dementia diagnosis confirmed according to ICD-10 (F00, F03, or G30), exclusion of vascular (F01) and secondary (F02) dementia

â–ª Dementia severity stages: MMSE: 0-9 severe; 10-17 moderate; 18-23 mild dementia

MMSE, ADAS (cognitive subscale), NOSGER (subscale mood), E-ADL

Diagnosis: confirmed by the attending physician

Screening instruments: Psychology students in their final year who had received training

[77]

[78]

[79]

[80]

Residents with dementia were identified using two combined inclusion criteria:

â–ª Presence of a dementia diagnosis; and

▪ MMSE < 24, GDS stadium 4, 5 or 6

▪ Exclusion criteria: presence of other neurological/psychiatric diseases that could explain patients’ decline in cognitive function (such as addiction, major depression, or schizophrenia)

Dementia diagnosis according to ICD-10 in the doctoral records

MMSE, GDS, ADAS (cognitive subscale), NOSGER (subscale mood), E-ADL

Not specified

[82]

Residents with dementia were identified using 2 combined inclusion criteria:

â–ª Existing diagnosis of dementia and

▪ MMSE ≤ 24

▪ Exclusion criteria: Korsakoff’s syndrome or CI caused by diseases other than dementia

No specified information given on the diagnostic procedure of the existing diagnosis

MMSE, CDR, AES

Not specified

[83]

Residents with dementia were identified using 2 combined inclusion criteria:

â–ª Admission criteria to the living unit were used as inclusion criteria (presence of a dementia diagnosis) and

â–ª MMSE < 18

No specified information given on the diagnostic procedure of the existing diagnosis

MMSE, NOSGER, GDS

Not specified

[84]

Residents with dementia were identified using two combined criteria:

â–ª Presence of a dementia diagnosis; and

▪ MMSE ≤ 27 and DemTect (scores of 6-8) for residents with a MMSE score between 24-27

â–ª No specified information given on the diagnostic procedure of the existing diagnosis

▪ Dementia severity stages: MMSE: ≤ 10 severely demented; 11-19 moderately demented, 20-27 mild dementia

MMSE, DemTect

Not specified

[85]

Residents with dementia were identified using 2 combined criteria:

▪ S-MMSE-Score ≤ 24

▪ Exclusion criteria: primary psychiatric diagnosis or Korsakov’s syndrome

â–ª No specified information given on the diagnostic procedure of the existing diagnosis

â–ª Different dementia severity stages were used

MMSE, NPI, Katz-Index

Formal diagnosis of dementia as determined by a healthcare professional (physician, psychiatrist, neurologist, geriatrician, general practitioner)

[86]

[87]

[88]

[89]

[90]

[47]

(Study Protocol)

Residents with dementia were identified using 2 combined criteria.

â–ª Medical diagnosis of dementia

â–ª FAST > 1

â–ª No specified information given on the diagnostic procedure of the existing Diagnosis

FAST, NPI, PSMS

â–ª Data were assessed by trained study assistants who interview two caregivers simultaneously

â–ª Study assistants (mainly students) undergo a 2-day training on the use of the questionnaires and receive a manual

â–ª The first data collection was assisted by senior and junior researchers

  1. AD Alzheimer’s disease, ADAS Alzheimer’s disease Assessment Scale, AES Apathy Evaluation Scale, CDR Clinical Dementia Rating, E-ADL Erlangen Test for Activities of Daily Living, FAST Functional Assessment Staging, GDS Global Deterioration Scale, MMSE Mini Mental State Examination, NOSGER Nurses’ Observation Scale, NPI Neuropsychiatric Inventory
  2. aThe reporting of instruments is not consistent across the publications. Therefore, all instruments used were summarized in this group. The studies also differ also regarding the criteria used to diagnose. Majic 2012 referred to DSM- IV, other publications to ICD-10
  3. bReporting of methods and proceedings slightly deviates from that of the other publications originating from this project (validation of recorded dementia diagnosis is not specified; MMSE cutoff 23; no exclusion criteria are reported)