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Table 1 Study procedures at various stages of the AVEC trial

From: The rationale and design of the antihypertensives and vascular, endothelial, and cognitive function (AVEC) trial in elderly hypertensives with early cognitive impairment: Role of the renin angiotensin system inhibition

Visit

Screen

Enrollment

Baseline

Titrate*

Follow-up

Months

0

2-4 weeks

1

2-3

3

6

12

Informed Consent/Eligibility

X

X

   

X

 

Medication Inventory

 

X

X

X

X

X

X

Weight/Height

  

X

  

X

X

Blood pressure

(2 every 5 min)

X

X

X

X

X

X

X

Psychological Assessment

X

 

X

  

X

X

Cerebrovascular Assessment

  

X

  

X

X

Biochemical Measures

 

X

 

X

X

X

X

Renin/Aldosterone

  

X

  

X

X

Adverse Events Screening

   

X

X

X

X

  1. If a titration of medication needed baseline will be performed after titration and before randomization