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Table 2 Alcohol-Interactive (AI) medication exposure, morbidity and prevalence of alcohol use by therapeutic class and morbidity (N = 3,815)

From: Potential for alcohol and drug interactions in older adults: evidence from the Irish longitudinal study on ageing

Characteristics

Exposure to AI medications

Alcohol use in individuals using AI medications in class

Alcohol use in individuals notusing AI medications in class

Total

 

%

%

%

P-value

Cardiovascular agents

61.2

60.4

67.0

<0.001

Angiotensin-receptor blockers & combinations

32.9

60.8

64.0

0.07

Beta blockers & combinations

19.5

57.5

64.3

0.001

Calcium channel blockers & combinations

13.7

57.8

63.8

0.01

Diuretics

12.5

53.5

64.3

<0.001

Alpha blockers

2.9

60.2

63.0

0.57

Vasodilator Antihypertensives

0.5

73.0

62.9

0.36

Nitrates

2.7

59.0

63.1

0.44

Cholesterol lowering agents

36.7

63.2

62.8

0.84

CNS agents

22.6

53.5

65.7

<0.001

NSAID

1.9

59.4

63.0

0.59

COX2 inhibitors

1.5

62.4

62.9

0.93

Opioid analgesics

3.1

51.8

63.3

0.02

Non-opioid analgesics

5.3

54.6

63.4

0.03

Anti-epileptics

2.8

50.2

63.3

0.008

Hypnotics

5.5

54.7

63.4

0.02

Anxiolytics

2.7

44.1

63.5

<0.001

Barbiturates

-

   

Antipsychotics

0.9

43.2

63.1

0.03

Antidepressants

7.4

52.9

63.8

0.002

Stimulants

-

-

-

 

Nausea and Vertigo

1.9

46.8

63.3

0.01

Antimigraine

-

-

-

 

Antiparkinson drugs

0.6

57.6

63.0

0.60

Dopaminergics

0.18

84.8

62.9

0.25

Drugs for dementia

0.46

   

Drugs for dependence

-

   

Antihistamines

0.9

66.9

62.9

0.65

Sedating

0.13

63.0

63.0

0.99

Non-sedating

0.84

65.0

62.9

0.82

Blood

34.2

58.5

65.3

<0.001

Anti-coagulant

3.6

55.9

63.2

0.09

Anti-platelet

31.0

58.8

64.8

0.001

Antidiabetic agents

7.2

53.8

63.7

0.002

Anti-infectives

0.2

47.0

63.0

0.43

Gastrointestinal drugs

1.2

49.5

63.1

0.09

Immunomodulators

1.0

50.7

63.1

0.10

Muscle relaxants

0.2

80.3

62.9

0.28

Other

3.0

69.6

62.8

0.18

Morbidity

Prevalence of condition

Alcohol use in individuals with condition

Alcohol use in individuals without condition

 
 

%

%

%

P-value

Diabetes

9.5

52.5

63.9

< 0.001

Hypertension

47.7

65.0

67.3

0.22

Peptic ulcer

7.1

60.8

63.0

0.49

Gout

1.9

74.5

62.7

0.08

Depression(CES-D ≥16)

7.7

57.7

63.5

0.06

Liver disease

0.54

39.7

62.9

0.04

Breast cancer

2.3

63.8

62.8

0.86

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BMC Geriatrics

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