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Volume 10 Supplement 1

de Senectute: Age and Health Forum

Sporadic Parkinsonism

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Differential diagnosis of parkinsonian sindrome is a major challenge in movement disorders because at the onset there is an overlapping of signs and syntoms. From a neuropathological point of view, parkinsonism may be related to a degeneration of the nigrostriatal pathway or the neurodegenerative process may be more widespread [1, 2]. In the early course of the a disease presenting with parkinsonian symptoms, differentiation between these disorders may be difficult, [3, 4], but the clinical diagnostic criteria become more applicable during later stages. Motor symptoms (bradikynesia, tremor at rest, rigidity) may be asoociated to cognitive disfunction. Sporadic parkinsonism may be distinguished in:) Multiple system atrophy (MSA), Progressive supranuclear palsy (PSP), Corticobasal degeneration, and Lewy body dementia [3, 5, 6].


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Correspondence to G Nicoletti.

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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution 2.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Nicoletti, G. Sporadic Parkinsonism. BMC Geriatr 10, L40 (2010) doi:10.1186/1471-2318-10-S1-L40

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  • Public Health
  • Dementia
  • Differential Diagnosis
  • Movement Disorder
  • Cognitive Disfunction