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Volume 10 Supplement 1

de Senectute: Age and Health Forum

  • Meeting abstract
  • Open Access

The Sequential Organ Failure Assessment (SOFA) score: a useful prognostic instrument after cardiac surgery for the elderly patient

  • 1,
  • 2,
  • 1,
  • 1,
  • 1,
  • 2,
  • 3,
  • 2 and
  • 1
BMC Geriatrics201010 (Suppl 1) :A99

https://doi.org/10.1186/1471-2318-10-S1-A99

  • Published:

Keywords

  • Intensive Care Unit
  • Organ Dysfunction
  • Intensive Care Unit Admission
  • Intensive Care Unit Patient
  • Sequential Organ Failure Assessment

Background

Organ dysfunction evaluation using Sequential Organ Failure Assessment score (SOFA score) has been shown to predict mortality and morbidity in adult cardiac surgical patients [1].

Materials and methods

Design: analysis of a prospectively collected database.

Setting: mixed Intensive Care Unit (ICU) in an University Hospital.

Patients: A total of 70 patients (ASA II-IV) aged >65 submitted to cardiac surgery. They were evaluated on 24,48 and 72 hours after ICU admission. All post-operative ASA IV-E (E= emergency) and all ICU patients with different diagnosis were excluded from data collection.

Interventions: the collection of raw data necessary for the computation of a SOFA score on 24, 48 and 72 hours after admission and basic demographic and clinical statistics.

Data collection: We collected the parameters in order to calculate the Admission (AD), Daily, Mean, Total Maximum (TM) and Delta (Δ) SOFA score at the specific time points mentioned above.

Results

The Admission, TMS score and Δ SOFA presented a good correlation with mortality [area under the curve 0,9 (SE 0,060) and 0,809 (SE 0,136), respectively]. All the patients that receive more than 2000 ml of intraoperative fluids had an Admission SOFA Score between 16 and 20 (p<0.001). All the patients with preoperative Left Ventricular Ejection Fraction > 45% had an Admission SOFA Score between 2 and 10 (p<0.001). All the patients mechanically ventilated for more than 5 days presented an Admission SOFA score between 17 and 20, while the same score was between 0 and 10 for those successfully extubated after 24 hours (p<0.001). The mean cardiovascular, coagulation, hepatic, neurological and renal SOFA score were associated with the highest relative contribution to outcome [area under the curve 0,980 (SE 0,028), 0,951 (SE 0,057), 0,927 (SE 0,069), 0,991 (SE 0,019) and 0,944 (SE 0,061), respectively].

Conclusions

SOFA score is a useful prognostic instrument even in this specific clinical context.

Authors’ Affiliations

(1)
Deparment of Anaesthesia and Reanimation, University of Catanzaro, Catanzaro, Italy
(2)
Department of Cardiac Surgery, University of Catanzaro, Catanzaro, Italy
(3)
Department of Anaesthesia and Oncological Intensive Care, Italy

References

  1. Pätilä T, Kukkonen S, Vento A, Pettilä V, Suojaranta-Ylinen R: Relation of the Sequential Organ Failure Assessment score to morbidity and mortality after cardiac surgery. Ann Thorac Surg. 2006, 82 (6): 2072-8. 10.1016/j.athoracsur.2006.06.025.PubMedView ArticleGoogle Scholar

Copyright

© Caroleo et al; licensee BioMed Central Ltd. 2010

This article is published under license to BioMed Central Ltd.

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