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Volume 10 Supplement 1

de Senectute: Age and Health Forum

  • Meeting abstract
  • Open Access

Piezo-electric surgery use for the management of patients with onj drug-induced: our experience

  • 1,
  • 1,
  • 1,
  • 1 and
  • 1
BMC Geriatrics201010 (Suppl 1) :A55

  • Published:


  • Osteoporosis
  • Bone Remodel
  • Sterile Saline
  • Hard Tissue
  • Osteoblastic Activity


Piezo-electric surgery is a procedure used recently in Oral-Maxillo-Facial Surgery [1]. The basic mechanisms are ultrasounds, that working in a frequency range between 25 and 30 Khz, determining very low oscillations on the tip of the handpiece, with effectiveness in cutting hard tissue but absolutely atraumatic on the soft tissue [2], with bio-stimulating effects. Piezo-electric cut takes place thanks to a modulate ultrasonic micro-vibration of 60-200 micro-meters of wideness, that it is able to cut all the mineralized tissues with the utmost respect to the soft tissue, impossible to damage even in an accidental contact. The bio-stimulation induces neo-angiogenesis, proliferation of epithelial tissue, increase of osteoblastic activity. In our Department of Maxillo-Facial Surgery a clinical study is ongoing whose aim is to demonstrate Piezo-Surgery validity as an adjuvant treatment for patient management in stage I (a,b), II (a,b) and stage IIIa (following the AAOMFS classification).

Materials and methods

From January 2003 to September 2009, 18 patients were treated with ONJ, 11 male and 7 female, range of age between 55 and 75. 16 of them have been cured with Zolendronic acid for cancer and 2 with Alendronic acid for osteoporosis. All the patients’ clinical conditions were classified following the AAOMFS.

Piezo-Surgery treatment has been carried out in more sessions and always under our protocol (Table 1). Small sequestrectomies and superficial debridements were performed with Piezo-Surgery in cutting mode and medium power; for the initial steps atraumatic rabbet or hooked cutting tips are necessary, that enable the removal and contemporary the bone remodeling. In a second phase atraumatic shaped ball tips were used for the soft tissue bio-stimulation with the Piezo-Surgery in standard mode. The entire surgical procedure needs abundant irrigation with sterile saline and broad-spectrum antibiotics.
Table 1

Anti-bacterial therapy

Amoxillina 1gr cp : 2 cp/die per 10 gg.

Clorexidina coll. 0,2%: rinses three times/day for 10 gg.

Nistatina 2-3 mis.die per 10 gg.

Metronidazolo cp 250 mg 2 cp per 4 die in 1 gg

Each cycle of therapy between the other has ten days of drug holiday


The results are indicated in Table.2: in 4 patients the results aren’t satisfactory; 10 patients are stationary; 3 patients improved (Figure 1); 1 patient has completely recovered (Figure 2).

Table 2

Patients Number

Initial Stage

Final stage






















* n. 10 clinical condition

# n. 4 worsted

^n. 3 improved

+n. 1 clinically free from Disease

Figure 1
Figure 1

Stage IIa to Ib, the clinical condition are improved after ten months of treatment

Figure 2
Figure 2

stage IIa to 0, clinical free from desease after ten months of treatment


PiezoSurgery carried out a clinical improvement of patients for its biostimulation effects.

Authors’ Affiliations

Department of Maxillofacial Surgery, Magna Graecia University, Catanzaro, Italy


  1. Eggers G, Klein J, Blank J, Hassfeld S: Piezosurgery: an ultrasound device for cutting bone and its use and limitation in maxillosurgery. British Journal of Oral and Maxillofacial Surgery. 2004, 42 (z): 451-453. 10.1016/j.bjoms.2004.04.006.PubMedView ArticleGoogle Scholar
  2. Beziat JL, Bera JC, Lavandier B, Gleizal A: Ultrasonic osteotomy as a new technique in craniomaxillofacialsurgery. Int. J. Oral Maxillofac.Surg. 2007, 36: 493-500. 10.1016/j.ijom.2007.01.012.PubMedView ArticleGoogle Scholar


© Cristofaro et al; licensee BioMed Central Ltd. 2010

This article is published under license to BioMed Central Ltd.