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Table 3 Outcome: Complaints, effect size, quality of life (estimated means and confidence intervals from the statistical model) in the study sample of older adults (> 70 years) under homeopathic treatment

From: Homeopathic treatment of elderly patients - a prospective observational study with follow-up over a two year period

STATUS

Month 0

Month 3

Month 12

Month 24

  

SEVERITY (NRS, All Diagnoses, Mean and 95% CI)

Complaintsa

6.27

(5.70; 6.84)

4.31

(3.71; 4.90)

4.41

(3.87; 4.95)

4.57

(4.03; 5.10)

  

Diagnosesb

6.57

(6.03; 7.11)

4.77

(4.23; 5.30)

4.63

(4.09; 5.16)

3.72

(3.19; 4.26)

  

QUALITY OF LIFE (SF-36 Component Scores, Mean and 95% CI)

Physical

38.37

(34.26; 42.47)

39.22

(35.11; 43.32)

38.86

(34.81; 42.90)

36.32

(32.29-40.35)

  

Mental

46.22

(41.56; 50.88)

49.59

(44.91; 54.27)

47.62

(43.04; 52.21)

46.02

(41.46; 50.58)

  

CHANGE c

 

Months 0-3

p c

Months 0-12

p c

Months 0-24

p c

SEVERITY (NRS, All Diagnoses, Mean and 95% CI)

Complaintsa

-1.96

(-2.67;-1.25)

< 0.001

-1.87

(-2.86; -0.88)

< 0.001

-1.71

(-2.83; -0.59)

< 0.001

Diagnosesb

-1.80

(-2.39; -1.21)

< 0.001

-1.94

(-2.71; -1.17)

< 0.001

-2.84

(-3.72; -1,96)

< 0.001

QUALITY OF LIFE (SF-36 Component Scores, Mean and 95% CI)

Physical

0.85

(-1.20; 2.90)

1.00

0.49

(-3.08; 4.06)

1.00

-2.05

(-6.86; 1.76)

1.00

Mental

3.37

(0,62; 6.12)

0.036

1.40

(-3.29; 6.09)

1.00

-0,20

(-6.41; 6.01)

1.00

STANDARDIZED MEAN CHANGE c

 

Months 0-3

p c

Months 0-12

p c

Months 0-24

p c

SEVERITY (NRS, All Diagnoses, Mean and 95% CI)

Complaintsa

-1.21

(-1.65; -0.77)

< 0.001

-1.15

(-1.76; -0.54)

< 0.001

-1.05

(-1.74; -0.36)

< 0.001

Diagnosesb

-1.08

(-1.44; -0.72)

< 0.001

-1.17

(-1.64; -0.70)

< 0.001

-1.72

(-2.25; -1.19)

< 0.001

QUALITY OF LIFE (SF-36 Component Scores, Mean and 95% CI)

Physical

0.05

(-0.07; 0.17)

1.00

0.03

(-0.17; 0.23)

1.00

-0.11

(-0.38; 0.16)

1.00

Mental

0.16

(0.02-0.30)

0.036

0.07

(-0.16; 0.30)

1.00

-0.01

(-0.32; 0.30)

1.00

  1. a Complaints = Patients' Assessment;b Diagnoses = Physicians' Assessment
  2. c p-values and confidence intervals were multiply adjusted to maintain an overall level of significance of 5%. However, due to the nature of this study they should only be interpreted as exploratory.
  3. NRS = Numerical Rating Scale: 10 = maximum, 0 = no complaints. Negative change in NRS indicates improvement. Positive quality of life change indicates improvement.
  4. Absolute effect size > 0.8, large; > 0.5, medium; > 0.2, small.